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Stimulation of Hedgehog (Hh) signaling induces carcinogenesis or promotes cell survival in cancers of multiple organs. In epithelial cancer with aberrant Hedgehog activation , abrogation of Hedgehog signaling by cyclopamine, a naturally occurring Hedgehog-specific small-molecule inhibitor, causes profound inhibition of tumor growth. In the present study,(More)
Expression of STENOFOLIA (STF) gene was analyzed in different organs of line R-108 barrel medic plants (Medicago truncatula Gaertn.). Maximum levels of STF expression were observed in the generative organs, fruits and flowers, suggesting its involvement in the reproduction process. The local analysis of STF expression during somatic embryogenesis in M.(More)
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