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Journals and Conferences
The role of the IL-17 pathway in antifungal host defense is controversial. Several studies suggested that IL-17 is crucial for the protection against Candida infection, whereas other studies reported that IL-17 may contribute to inflammatory pathology and worsening of fungal disease. To address these discrepancies, we assessed the differential role of IL-17… (More)
White leghorn cockerels of the same age with combs of about equal size and raised under identical conditions were injected with melatonin, 5-methoxytryptophol, or with 5-methoxytryptophol in combination with melatonin. Melatonin, injected in animals with small comb sizes, has no effect on testicular growth, whereas an inhibiting effect is noticed in animals… (More)
The reactionproduct of arginine with 2,4-dichloro-α-naphthol proved to be fluorescent. This fluorescence could be used for the histochemical localization of arginine. The modification described resulted in a long lasting yellow-orange fluorescence of various arginine-containing tissues.
Melanophores from tadpoles of Xenopus laevis (Daudin) were isolated by digestion of tail fins with acetyltrypsin and collagenase and maintained in primary culture for 6 weeks up to 3 months. Within 36 to 72 h the melanophores develop one to eight dendritic processes per cell; secondary and tertiary branchings of the processes were frequently observed. The… (More)
Pigment of tail-fin melanophores in periodic albino Xenopus laevis tadpoles is dispersed in response to darkness and to α-MSH in a manner similar to wild-type melanophores. However, periodic albino tadpoles lack the response to different background conditions and the melatonin-induced aggregation in darkness. The tyrosinase activity in cells of the latter… (More)
Tail-fin melanophores of tadpoles of Xenopus laevis (Daudin) in primary culture were examined scanning electron microscopically in the aggregated and in the dispersed state. After isolation, the melanophores are spherical, but within 24 h they develop thin filopodia for attachment to the substratum. Subsequently, cylinder-like as well as flat sheet-like… (More)
Administration of 5-methoxytryptophol (5-MTL) in juvenile, maturing and adult white leghorn hens causes age dependent effects. In juvenile birds ovarian growth is stimulated, while in maturing animals this is inhibited. In adult experimental hens ovarian weight is not significantly different from that of the control animals. Follicular weight, however, is… (More)
Mit Hilfe chemischer und histochemischer Technik gelingt in der Haut vonXenopus laevis der Nachweis eines dopamingefüllten Reservoirs. Das Catecholamin ist mit der physiologischen Melanophorenreaktion verbunden.
Die Verwendung von 1N Natronlauge und Essigsäureanhydrid bei der Bestimmung von Indolderivaten mit Hilfe der Fluoreszenzmethode erlaubt eine gute Differenzierung zwischen 5-Methoxyindolderivaten (z.B. Melatonin) und anderen Indolen. Versuche zur Verwendung der neuen Methode in biologischem Material, z.B. Epiphysenschnitten, sind im Gange.
The melanocyte-stimulating substance, found in the dorsal skin secretion of Xenopus laevis, has been identified as 5-hydroxytryptamine (serotonin).