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Surgical Correction of Anatomic Abnormalities in Obstructive Sleep Apnea Syndrome: Uvulopalatopharyngoplasty
- S. Fujita, William Conway, F. Zorick, T. Roth
- MedicineOtolaryngology--head and neck surgery : official…
- 1 November 1981
A new surgical approach to treat obstructive sleep apnea by uvulopalatopharyngoplasty designed to enlarge the potential airspace in the oropharynx, which shows objective improvement in nocturnal respiration and sleep pattern.
Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients.
It is concluded that OSA patients with an apnea index of greater than 20 have a greater mortality than those below 20 and that UPPP patients be restudied after therapy and if the latter patients are found not to have marked amelioration of their AI, then they should be treated by nasal CPAP or tracheostomy.
Sleep fragmentation and daytime sleepiness.
The number and type of nocturnal arousals play an important role in subsequent daytime sleepiness and, depending upon the sleep complaint, different types of arousals are predictive of degree of daytimeSleepiness.
Sleep disorders in patients on continuous ambulatory peritoneal dialysis.
- E. Stepanski, M. Faber, F. Zorick, R. Basner, T. Roth
- Medicine, PsychologyJournal of the American Society of Nephrology…
- 1 August 1995
The presence of sleep apnea was associated with increased levels of psychological distress and daytime sleepiness, and periodic leg movements during sleep were frequently observed but had minimal effect on sleep quality.
Multiple naps and the evaluation of daytime sleepiness in patients with upper airway sleep apnea.
Another measure of daytime sleepiness which is not dependent on the patient's subjective response is clearly needed, and the Stanford group recently introduced the MUltiple Sleep Latency Test.
Heart rate changes in chronic insomnia
This study assessed physiological activity in patients with chronic insomnia before sleep, during sleep and in response to acute stress. Twenty-four subjects with chronic insomnia and 25 normal…
Daytime alertness in patients with chronic insomnia compared with asymptomatic control subjects.
The results are interpreted as supporting the existence of a tendency towards physiological hyperarousal in patients with chronic insomnia, which may be exacerbated by other factors also associated with insomnia.
Sleepiness and ethanol effects on simulated driving.
- T. Roehrs, D. Beare, F. Zorick, T. Roth
- MedicineAlcoholism, clinical and experimental research
- 1 February 1994
The results show that sleepiness and low-dose ethanol combine to impair simulated automobile driving, an impairment that extends beyond the point at which BEC reaches zero, a possible explanation for the incidence of alcohol-related automobile accidents at low BECs.
The Dose Effects of Zolpidem on the Sleep of Healthy Normals
- L. Merlotti, T. Roehrs, G. Koshorek, F. Zorick, J. Lamphere, T. Roth
- Medicine, PsychologyJournal of clinical psychopharmacology
- 1 February 1989
Zolpidem was hypnotically active at doses as low as 5.0 and 7.5 mg, andSleep stage effects occurred only at the 20 mg dose, thus separating the dose range of hypnotic and sleep stage effects.
Predictors of objective level of daytime sleepiness in patients with sleep-related breathing disorders.
The hypothesis that sleep fragmentation is an important determinant of daytime sleepiness in patients with apnea is supported.