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Role of Transforming Growth Factor-β in Long-Term Synaptic Facilitation in Aplysia
The role of transforming growth factor-β (TGF-β) in long-term synaptic facilitation was examined in isolated Aplysia ganglia. Treatment with TGF-β1 induced long-term facilitation (24 and 48 hours),… Expand
Neurochemical Plasticity of Nitric Oxide Synthase Isoforms in Neurogenic Detrusor Overactivity after Spinal Cord Injury
Nitric oxide (NO) participates in the neural pathways controlling the lower urinary tract (LUT). Expression of NO synthase (NOS) can be upregulated after spinal cord injury (SCI), and altered NOS… Expand
Role of calcium-calmodulin-dependent protein kinase II in modulation of sensorimotor synapses in Aplysia.
- K. Nakanishi, F. Zhang, D. A. Baxter, A. Eskin, J. Byrne
- Chemistry, Medicine
- Journal of neurophysiology
- 1 July 1997
The Ca2+-calmodulin-dependent protein kinase II (CaMKII) inhibitor, [1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne) (KN-62), was used to investigate the role of CaMKII in… Expand
Neural analogue of long-term sensitization training produces long-term (24 and 48 h) facilitation of the sensory-to-motor neuron connection in Aplysia.
1. An in vitro analogue of long-term sensitization training was used to gain insights into the mechanisms and time course of the memory for long-term sensitization in Aplysia. The analogue,… Expand
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
To define the cell populations that drive joint inflammation in rheumatoid arthritis (RA), we applied single-cell RNA sequencing (scRNA-seq), mass cytometry, bulk RNA sequencing (RNA-seq) and flow… Expand
Propofol inhibits inflammatory cytokine-mediated glutamate uptake dysfunction to alleviate learning/memory impairment in depressed rats undergoing electroconvulsive shock
Electroconvulsive therapy (ECT) is an effective treatment for major depression, but can result in memory impairment. Several studies have shown that anesthetic propofol can alleviate the impairment… Expand
SlicerDMRI: Open Source Diffusion MRI Software for Brain Cancer Research.
- I. Norton, Walid I. Essayed, +12 authors L. O'Donnell
- Medicine, Computer Science
- Cancer research
- 1 November 2017
We describe SlicerDMRI, a software suite that enables visualization and analysis of dMRI for neuroscientific studies and patient-specific anatomic assessment. Expand
Multimodal neuroimaging computing: a review of the applications in neuropsychiatric disorders.
Multimodal neuroimaging is increasingly used in neuroscience research, as it overcomes the limitations of individual modalities. One of the most important applications of multimodal neuroimaging is… Expand
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 and other diseases with tissue inflammation
- F. Zhang, Joseph R. Mears, +6 authors S. Raychaudhuri
- Medicine, Biology
- bioRxiv : the preprint server for biology
- 5 August 2020
Immunosuppressive and anti-cytokine treatment may have a protective effect for patients with COVID-19. Understanding the immune cell states shared between COVID-19 and other inflammatory diseases… Expand
POSITIONAL DISCRIMINATION AND RE-DEVELOPMENT OF SYNAPSES IN THE LEECH WHITMANIA PIGRA
Summary Identified neurones in the leech Whitmania pigra have a stable morphology with bilaterally symmetrical branching arborizations, and with axons on both sides arranged symmetrically in the… Expand