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Effect of BDNF Val66Met Polymorphism on Digital Working Memory and Spatial Localization in a Healthy Chinese Han Population
Cognitive abilities are complex human traits influenced by genetic factors. Brain-derived neurotrophic factor (BDNF), a unique polypeptide growth factor, has an influence on the differentiation andExpand
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An association study between cathechol-O-methyltransferase gene and mental retardation in the Chinese Han population
Cathechol-O-methyltransferase (COMT) regulates the amount of dopamine in the prefrontal cortex (PFC). Substantial studies indicate a close relationship between COMT and several human psychoticExpand
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Positive association of the FTSJ1 gene polymorphisms with nonsyndromic X-linked mental retardation in young Chinese male subjects
AbstractTo investigate the possible genetic association of nonsyndromic X-linked mental retardation (NS-XLMR) with FTSJ1 gene polymorphisms, a case–control association study was performed focusing onExpand
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The Effects of DBH, MAOA, and MAOB on Attentional Biases for Facial Expressions
Attentional bias is the interaction that occurs between emotion and attention. Monoamine oxidase and dopamine β-hydroxylase are involved in the balances of neurotransmitters in the cortex. MuchExpand
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Variations in 5-HT2A influence spatial cognitive abilities and working memory.
BACKGROUND 5-hydroxytryptamine receptor 2A (5-HT2A) participates in diverse psychiatric disorders by regulating the activity of serotonin. Some previous studies have also suggested that the receptorExpand
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An Association Study on the Polymorphisms of Dopaminergic Genes with Working Memory in a Healthy Chinese Han Population
Working memory (WM) is a highly heritable cognitive trait that is involved in many higher-level cognitive functions. In the past few years, much evidence has indicated that the reduction of dopamineExpand
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Psoriasis is one of the most common skin diseases in the world. In 1984, a cooperative epidemiologic study of psoriasis, the first on a large scale with a uniform survey method and criteria, wasExpand
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Positive association of neuroligin-4 gene with nonspecific mental retardation in the Qinba Mountains Region of China
Objective Neuroligin-4 is essential for proper brain function. Some studies indicate a close relationship between neuroligin-4 and several human psychiatric conditions. Methods The case–controlExpand
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Variants in COMT and DBH Influence on Response Inhibition Ability in Chinese Han Females
Catechol-O-methyltransferase (COMT) and dopamine-beta hydroxylase (DBH) are key enzymes to breakdown dopamine. Some previous studies have indicated that val158met in COMT and 19 bp insertion/deletionExpand
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