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A microfluidics-based in vitro model of the gastrointestinal human–microbe interface
Changes in the human gastrointestinal microbiome are associated with several diseases. To infer causality, experiments in representative models are essential, but widely used animal models exhibit… Expand
BIODOSIMETRY ON SMALL BLOOD VOLUME USING GENE EXPRESSION ASSAY
This paper reports the development of a biodosimetry device suitable for rapidly measuring expression levels of a low-density gene set that can define radiation exposure, dose and injury in a public… Expand
Laboratory Intercomparison of Gene Expression Assays
The possibility of a large-scale acute radiation exposure necessitates the development of new methods that could provide rapid individual dose estimates with high sample throughput. The focus of the… Expand
Paper-based Vertical Flow Immunoassay (VFI) for detection of bio-threat pathogens.
Currently, the standard method for identifying biological agents of potential threats to national security and public health, such as pathogens, virus, and toxins, mainly rely on microbiological… Expand
Comparison of Established and Emerging Biodosimetry Assays
Rapid biodosimetry tools are required to assist with triage in the case of a large-scale radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well-established dicentric… Expand
The vaginal and gastrointestinal microbiomes in gynecologic cancers: a review of applications in etiology, symptoms and treatment.
- D. Chase, A. Goulder, F. Zenhausern, B. Monk, M. Herbst-Kralovetz
- Gynecologic oncology
- 1 July 2015
The human microbiome is the collection of microorganisms in the body that exist in a mutualistic relationship with the host. Recent studies indicate that perturbations in the microbiome may be… Expand
Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review
Purpose To compile a list of genes that have been reported to be affected by external ionizing radiation (IR) and to assess their performance as candidate biomarkers for individual human radiation… Expand
Analysis of Saliva Gene Expression during Head and Neck Cancer Radiotherapy: A Pilot Study
Saliva, a biological fluid, is a promising candidate for novel approaches to prognosis, clinical diagnosis, monitoring and management of patients with both oral and systemic diseases. However, to… Expand
Radiogenomics: radiobiology enters the era of big data and team science.
- B. Rosenstein, C. West, +35 authors F. Zenhausern
- International journal of radiation oncology…
- 15 July 2014
Reprint requests to: Barry S. Rosenstein,PhD, Department of RadiationOncology, Icahn School of Medicine at Mount Sinai, One Gustave L. LevyPlace, Box 1236, New York, NY 10029. Tel: (212) 824-8960;… Expand
Emergence of miR-34a in radiation therapy.
Expressions of many microRNAs (miRNAs) in response to ionizing radiation (IR) have already been investigated and some of them seem to play an important role in the tumor radioresistance, normal… Expand