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Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species.
During inflammation, NF-kappaB transcription factors antagonize apoptosis induced by tumor necrosis factor (TNF)alpha. This antiapoptotic activity of NF-kappaB involves suppressing the accumulationExpand
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Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species
Abstract During inflammation, NF-κB transcription factors antagonize apoptosis induced by tumor necrosis factor (TNF)α. This antiapoptotic activity of NF-κB involves suppressing the accumulation ofExpand
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Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling
In addition to coordinating immune and inflammatory responses, NF-κB/Rel transcription factors control cell survival. Normally, NF-κB dimers are sequestered in the cytoplasm by binding to inhibitoryExpand
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Induction of gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling.
In addition to coordinating immune and inflammatory responses, NF-kappaB/Rel transcription factors control cell survival. Normally, NF-kappaB dimers are sequestered in the cytoplasm by binding toExpand
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Gadd45β mediates the NF-κB suppression of JNK signalling by targeting MKK7/JNKK2
NF-κB/Rel transcription factors control apoptosis, also known as programmed cell death. This control is crucial for oncogenesis, cancer chemo-resistance and for antagonizing tumour necrosis factor αExpand
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The NF-kappaB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease.
NF-kappaB/Rel transcription factors have recently emerged as crucial regulators of cell survival. Activation of NF-kappaB antagonizes programmed cell death (PCD) induced by tumor necrosisExpand
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Gadd45 beta mediates the NF-kappa B suppression of JNK signalling by targeting MKK7/JNKK2.
NF-kappa B/Rel transcription factors control apoptosis, also known as programmed cell death. This control is crucial for oncogenesis, cancer chemo-resistance and for antagonizing tumour necrosisExpand
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Linking JNK signaling to NF-κB: a key to survival
In addition to marshalling immune and inflammatory responses, transcription factors of the NF-κB family control cell survival. This control is crucial to a wide range of biological processes,Expand
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The Inflammatory Microenvironment in Hepatocellular Carcinoma: A Pivotal Role for Tumor-Associated Macrophages
Hepatocellular carcinoma (HCC) is one of the most common and aggressive human cancers worldwide. HCC is an example of inflammation-related cancer and represents a paradigm of the relation occurringExpand
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The NF-κB-mediated control of the JNK cascade in the antagonism of programmed cell death in health and disease
NF-κB/Rel transcription factors have recently emerged as crucial regulators of cell survival. Activation of NF-κB antagonizes programmed cell death (PCD) induced by tumor necrosis factor-receptorsExpand
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