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A preliminary study
TLDR
CEUS can help RMI to make a more effective differential diagnosis of the adnexal mass and further validation by additional multicenter prospective trials is required. Expand
Effect of iodine intake on thyroid diseases in China.
TLDR
More than adequate or excessive iodine intake may lead to hypothyroidism and autoimmune thyroiditis in cohorts from three regions with different levels of iodine intake. Expand
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
TLDR
A case-control genome-wide association study offers the potential to improve the safety profile of lumiracoxib by identifying individuals at elevated risk for liver injury and excluding them from lumirACoxib treatment. Expand
MicroRNA-34a Targets Bcl-2 and Sensitizes Human Hepatocellular Carcinoma Cells to Sorafenib Treatment
TLDR
This study is the first to demonstrate that miR-34a induces sensitivity to the anti-tumor effect of sorafenib in human HCC cells, suggesting a potential role of miR -34a in the treatment of HCC. Expand
Regulation of homocysteine metabolism and methylation in human and mouse tissues
TLDR
This study is the first to provide panoramic tissue gene expression profiles and mathematical models of tissue methylation regulation and established equations expressing combined effects of methylation enzymes on tissue SAH, SAM, and SAM/SAH ratios. Expand
Mutation at cleavage site of insulin-like growth factor receptor in a short-stature child born with intrauterine growth retardation.
TLDR
These findings strongly suggest that this mutation leads to failure of processing of the IGF-IR proreceptor to mature IGF- IR and causes short stature and IUGR. Expand
Comparison of Epidermal Growth Factor Receptor Mutation Statuses in Tissue and Plasma in Stage I–IV Non-Small Cell Lung Cancer Patients
TLDR
The aims of this study were to determine the specific subgroups of NSCLC patients who may be the best candidates for EGFR mutation analyses using blood cfDNA and to compare the mutation statuses in plasma to those in tissues. Expand
Surgical treatment of primary palmar hyperhidrosis: a prospective randomized study comparing T3 and T4 sympathicotomy.
TLDR
T4 sympathicotomy, decreases the side effects but do not compromise the therapeutic effects, and should be the method of choice for the treatment of PH. Expand
Expression profile analysis of long noncoding RNA in HER-2-enriched subtype breast cancer by next-generation sequencing and bioinformatics
TLDR
The functions of LncRNAs are analyzed and provide useful information for exploring candidate therapeutic targets and new molecular biomarkers for HER-2-enriched subtype breast cancer. Expand
Prevalence of Nontraumatic Osteonecrosis of the Femoral Head and its Associated Risk Factors in the Chinese Population: Results from a Nationally Representative Survey
TLDR
It is highlighted that NONFH is a significant public health challenge in China and underscore the need for policy measures on the national level as high blood levels of triglycerides, total cholesterol, LDL-ch cholesterol, and non-HDL-cholesterol, male, urban residence, family history of osteonecrosis of the femoral head, heavy smoking, alcohol abuse and glucocorticoid intake, overweight, and obesity were all significantly associated with an increased risk of NONFH. Expand
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