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Structure of an Agonist-Bound Human A2A Adenosine Receptor
Changes associated with conformationally selective agonist binding shed light on G protein–coupled receptor activation. Activation of G protein–coupled receptors upon agonist binding is a critical… Expand
Structural Basis for Allosteric Regulation of GPCRs by Sodium Ions
GPCR Close-Up Structures of G protein–coupled receptors (GPCRs) determined in the past few years, have provided insight into the function of this important family of membrane proteins. Liu et al. (p.… Expand
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors.
Structural studies of human G protein-coupled receptors (GPCRs) have recently been accelerated through the use of a fusion partner that was inserted into the third intracellular loop. Using chimeras… Expand
Core structure of the yeast spt4-spt5 complex: a conserved module for regulation of transcription elongation.
The Spt4-Spt5 complex is an essential RNA polymerase II elongation factor found in all eukaryotes and important for gene regulation. We report here the crystal structure of Saccharomyces cerevisiae… Expand
Molecular mapping of Arabidopsis thaliana lipid-related orthologous genes in Brassica napus
- J. Zhao, J. Huang, +10 authors J. Meng
- Biology, Medicine
- Theoretical and Applied Genetics
- 1 February 2012
Quantitative Trait Loci (QTL) for oil content has been previously analyzed in a SG-DH population from a cross between a Chinese cultivar and a European cultivar of Brassica napus. Eight QTL with… Expand
Design and preparation of porous polymers.
- Dingcai Wu, F. Xu, Bin Sun, R. Fu, H. He, K. Matyjaszewski
- Chemistry, Medicine
- Chemical reviews
- 17 May 2012
Dingcai Wu,*,† Fei Xu,† Bin Sun,† Ruowen Fu,† Hongkun He,‡ and Krzysztof Matyjaszewski*,‡ †Materials Science Institute, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of… Expand
Structural Basis for Apelin Control of the Human Apelin Receptor.
Apelin receptor (APJR) is a key regulator of human cardiovascular function and is activated by two different endogenous peptide ligands, apelin and Elabela, each with different isoforms diversified… Expand
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand
The Smoothened receptor (SMO) belongs to the Class Frizzled of the G protein-coupled receptor (GPCR) superfamily, constituting a key component of the Hedgehog signalling pathway. Here we report the… Expand
DNA Architecture, Deformability, and Nucleosome Positioning
Abstract The positioning of DNA on nucleosomes is critical to both the organization and expression of the genetic message. Here we focus on DNA conformational signals found in the growing library of… Expand
Longitudinal piezoelectric coefficient measurement for bulk ceramics and thin films using pneumatic pressure rig
A pneumatic pressure rig was designed to measure the effective d33 coefficient of thin film piezoelectrics by applying a known stress and monitoring the induced charge. It was found that the stress… Expand