• Publications
  • Influence
Oxidation of phenols, anilines, and benzenethiols by fungal laccases: correlation between activity and redox potentials as well as halide inhibition.
  • F. Xu
  • Chemistry, Medicine
  • Biochemistry
  • 11 June 1996
A comparative study has been performed with several fungal laccases for the oxidation of a series of phenols, anilines, and benzenethiols and for the inhibition by halides. The observed K(m) and kcatExpand
  • 607
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A study of a series of recombinant fungal laccases and bilirubin oxidase that exhibit significant differences in redox potential, substrate specificity, and stability.
A series of fungal laccases (Polyporus pinsitus, Rhizoctonia solani, Myceliophthora thermophila, Scytalidium thermophilum) and one bilirubin oxidase (Myrothecium verrucaria) have been studied toExpand
  • 491
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LRP/Amyloid β-Peptide Interaction Mediates Differential Brain Efflux of Aβ Isoforms
Abstract LRP (low-density lipoprotein receptor-related protein) is linked to Alzheimer's disease (AD). Here, we report amyloid β-peptide Aβ40 binds to immobilized LRP clusters II and IV with highExpand
  • 617
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Effects of Redox Potential and Hydroxide Inhibition on the pH Activity Profile of Fungal Laccases*
  • F. Xu
  • Chemistry, Medicine
  • The Journal of Biological Chemistry
  • 10 January 1997
The electronic absorption spectrum, susceptibility to fluoride inhibition, redox potential, and substrate turnover of several fungal laccases have been explored as a function of pH. The laccasesExpand
  • 357
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LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.
LRP (low-density lipoprotein receptor-related protein) is linked to Alzheimer's disease (AD). Here, we report amyloid beta-peptide Abeta40 binds to immobilized LRP clusters II and IV with highExpand
  • 351
  • 24
Early-onset and Robust Cerebral Microvascular Accumulation of Amyloid β-Protein in Transgenic Mice Expressing Low Levels of a Vasculotropic Dutch/Iowa Mutant Form of Amyloid β-Protein Precursor*
Cerebrovascular deposition of amyloid β-protein (Aβ) is a common pathological feature of Alzheimer's disease and related disorders. In particular, the Dutch E22Q and Iowa D23N mutations in Aβ causeExpand
  • 285
  • 24
NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas.
  • Y. Yu, F. Xu, +9 authors R. Bast
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 5 January 1999
Using differential display PCR, we have identified a gene [NOEY2, ARHI (designation by the Human Gene Nomenclature Committee)] with high homology to ras and rap that is expressed consistently inExpand
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AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.
To explore the genetic abnormalities that cooperate with AML1-ETO (AE) fusion gene to cause acute myeloid leukemia (AML) with t(8;21), we screened a number of candidate genes and identified 11 typesExpand
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Characterization of lignin structures and lignin-carbohydrate complex (LCC) linkages by quantitative 13C and 2D HSQC NMR spectroscopy.
To characterize the lignin structures and lignin-carbohydrate complex (LCC) linkages, milled wood lignin (MWL) and mild acidolysis lignin (MAL) with a high content of associated carbohydrates wereExpand
  • 304
  • 17
Site-directed mutations in fungal laccase: effect on redox potential, activity and pH profile.
A Myceliophthora thermophila laccase and a Rhizoctonia solani laccase were mutated on a pentapeptide segment believed to be near the type-1 Cu site. The mutation L513F in Myceliophthora laccase andExpand
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