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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- M. Hammerschlag, C. Dykstra, D. Vandewiele
- Computer ScienceAntimicrobial Agents and Chemotherapy
- 1 January 2007
The introduction should supply sufficient background information to allow the reader to understand and evaluate the results of the present study without referring to previous publications on the topic.
Subcellular localization of oxidosqualene cyclases from Arabidopsis thaliana, Trypanosoma cruzi, and Pneumocystis carinii expressed in yeast
Computer analysis supports the hypothesis of the structural difference since OSC from S. cerevisiae, A. thaliana, and T. carinii differ in some structural features critical for the interaction with the surface of lipid particles.
Characterization and partial purification of squalene-2,3-oxide cyclase from Saccharomyces cerevisiae.
Yeast Oxidosqualene Cyclase (Erg7p) Is a Major Component of Lipid Particles*
Evidence is provided that lipid particles are not only a depot for neutral lipids, but also participate in coordinate sterol metabolism and trafficking and serve as a storage site for compounds that may negatively affect membrane integrity.
Regulation of HMGCoA Reductase Activity by Policosanol and Octacosadienol, a New Synthetic Analogue of Octacosanol
Octacosadienol was as effective as policosanol in inhibiting the upregulation of HMG coA reductase, in inducing the phosphorylation of AMPK and in downregulating the HMGCoA reduCTase mRNA.
Inhibition of the ROS-mediated cytotoxicity and genotoxicity of nano-TiO2 toward human keratinocyte cells by iron doping
Nano-TiO2 powders are widely used in sunscreen lotions as UV filters in combination with other substances. The activation of TiO2 by UV rays leads to the release of reactive oxygen species (ROS,…
The transformation of 10α-cucurbita-5,24-dien-3β-ol into cucurbitacin C by seedlings of Cucumis sativus
Side chain degradation and microbial reduction of different steroids by Aspergillus auroefulgens.
Cyclization of squalene-2,3-epoxide to 10α-cucurbita-5,24-dien-3β-ol by microsomes from Cucurbita maxima seedlings