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Using voxel-based morphometry to map the structural changes associated with rapid conversion in MCI: A longitudinal MRI study
TLDR
A novel longitudinal voxel-based method is used to map the progression of GM loss in MCI patients over time and compared converters to non-converters to better understand the pathological processes underlying AD and to monitor the effects of treatment on brain structure. Expand
Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission.
TLDR
Prophylactic cranial irradiation given to patients with small-cell lung cancer in complete remission decreases the risk of brain metastasis threefold without a significant increase in complications. Expand
Mapping gray matter loss with voxel-based morphometry in mild cognitive impairment
TLDR
This pattern of gray matter loss in mild cognitive impairment agrees with but considerably expands upon previous region-of-interest based MRI studies, and is highly consistent with the course of neurofibrillary tangles across aging and Alzheimer's disease. Expand
Relationships between Hippocampal Atrophy, White Matter Disruption, and Gray Matter Hypometabolism in Alzheimer's Disease
TLDR
It is found that hippocampal atrophy is specifically related to cingulum bundle disruption, which is in turn highly correlated to hypometabolism of the posterior cingulate cortex but also of the middle cingulates gyrus, thalamus, mammillary bodies, parahippocampal gyrus and hippocampus, as well as the right temporoparietal associative cortex. Expand
Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging
TLDR
The lesser affected anterior hippocampal region appears to mark the parting of the ways between normal aging and Alzheimer's disease, which is characterized by early and prominent deterioration of both structures. Expand
Direct voxel-based comparison between grey matter hypometabolism and atrophy in Alzheimer's disease.
TLDR
The hypometabolism significantly exceeded atrophy in most altered structures, particularly in the posterior cingulate-precuneus, orbitofrontal, inferior temporo-parietal, parahippocampal, angular and fusiform areas. Expand
Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis.
TLDR
In this study of patients with symptomatic carotid stenosis of 60% or more, the rates of death and stroke at 1 and 6 months were lower with endarterectomy than with stenting. Expand
What does transient global amnesia really mean? Review of the literature and thorough study of 142 cases.
TLDR
This paper reported 142 personal TGA cases, and suggested the existence of different groups of TGA patients, on the basis of a hierarchical cluster analysis, which revealed that in women, episodes are mainly associated with an emotional precipitating event, a history of anxiety and a pathological personality. Expand
Endarterectomy versus stenting in patients with symptomatic severe carotid stenosis
TLDR
In this study of patients with symptomatic carotid stenosis of 60% or more, the rates of death and stroke at 1 and 6 months were lower with endarterectomy than with stenting. Expand
Mild cognitive impairment
TLDR
It is suggested that among patients with MCI, fluorodeoxyglucose PET may accurately identify rapid converters, and replication in an independent sample is needed to confirm this finding. Expand
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