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A forkhead-domain gene is mutated in a severe speech and language disorder
Individuals affected with developmental disorders of speech and language have substantial difficulty acquiring expressive and/or receptive language in the absence of any profound sensory orExpand
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Identification of FOXP2 truncation as a novel cause of developmental speech and language deficits.
FOXP2, the first gene to have been implicated in a developmental communication disorder, offers a unique entry point into neuromolecular mechanisms influencing human speech and language acquisition.Expand
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Localisation of a gene implicated in a severe speech and language disorder
TLDR
We have identified a region on chromosome 7 which co-segregates with the KE family, a large three-generation pedigree in which approximately half of the members are affected with a severe speech and language disorder which appears to be transmitted as an autosomal dominant monogenic trait. Expand
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Differential course of development of spatial and verbal memory span: A normative study
Children ranging from 7 to 15 were given memory span tests for both digits and blocks, each consisting of forward and backward recall components. Both types of span showed developmental increases.Expand
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The SPCH1 region on human 7q31: genomic characterization of the critical interval and localization of translocations associated with speech and language disorder.
The KE family is a large three-generation pedigree in which half the members are affected with a severe speech and language disorder that is transmitted as an autosomal dominant monogenic trait. InExpand
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Development of speech and language following bilateral frontal lesions
Language and speech were studied in a young child with perinatally acquired bifrontal lesions. Bilateral frontal pathology seriously interfered with the development of intelligible speech andExpand
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H magnetic resonance spectroscopy in the investigation of intractable epilepsy
We have been using proton magnetic resonance spectroscopy (1H MRS) in the investigation of adults and children with intractable epilepsy. Spectra were obtained from 2 × 2 times 2 cm cubes in theExpand
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Cerebral asymmetry in infants
Abstract Two experiments were conducted to replicate the reported finding ( A. K. Entus, 1977 , In S. J. Segalowitz and F. Gruber, Eds., Language development and neurological theory, New York:Expand
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