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Enhanced responses of blood pressure, renal function, and aldosterone to angiotensin I in the DD genotype are blunted by low sodium intake.
- F. V. D. van der Kleij, P. D. de Jong, R. H. Henning, D. de Zeeuw, G. Navis
- Journal of the American Society of Nephrology…
- 1 April 2002
Angiotensin-converting enzyme (ACE) activity is increased in the DD genotype, but the functional significance for renal function is unknown. Blunted responses of BP and proteinuria to ACE inhibition… Expand
Angiotensin converting enzyme insertion/deletion polymorphism and short-term renal response to ACE inhibition: role of sodium status.
- F. V. D. van der Kleij, A. Schmidt, +5 authors D. de Zeeuw
- Kidney international. Supplement
- 1 December 1997
Angiotensin converting enzyme (ACEi) inhibition retards renal function loss, but the therapeutic benefit varies between individuals. Renoprotection is poor in patients with the ACE DD genotype. ACE… Expand
Effect of loxiglumide and atropine on erythromycin‐induced reduction in gallbladder volume in human subjects
This study was undertaken to investigate the effect of erythromycin, a motilin agonist with prokinetic activity, on fasting gallbladder volume. To evaluate the mechanism of action of erythromycin on… Expand
Angiotensin-converting enzyme gene I/D polymorphism and renal disease
- G. Navis, F. V. D. van der Kleij, D. de Zeeuw, P. D. de Jong
- Biology, Medicine
- Journal of Molecular Medicine
- 9 November 1999
In recent years a vast amount of data has been published on the association between the insertion/deletion (I/D) polymorphism of the gene coding for angiotensin-converting enzyme and renal disease.… Expand
Short-term moderate sodium restriction induces relative hyperfiltration in normotensive normoalbuminuric Type I diabetes mellitus
Aims/hypothesis. Type I (insulin-dependent) diabetes mellitus is associated with an increased extracellular volume. Sodium restriction might seem a logical form of treatment but data on its renal… Expand
Salt loading affects cortisol metabolism in normotensive subjects: relationships with salt sensitivity.
- M. Kerstens, F. V. D. van der Kleij, +4 authors R. Dullaart
- The Journal of clinical endocrinology and…
- 1 September 2003
We studied cortisol metabolism together with insulin sensitivity [homeostatic model assessment (HOMA)] and renal hemodynamics in 19 salt-resistant (sr) and nine salt-sensitive (ss) normotensive… Expand
Adult respiratory distress syndrome due to pheochromocytoma as the initial presentation of multiple endocrine neoplasia type IIA syndrome.
- F. V. D. van der Kleij
- The American journal of medicine
ACE polymorphism does not determine short-term renal response to ACE-inhibition in proteinuric patients.
- F. V. D. van der Kleij, G. Navis, +4 authors P. D. de Jong
- Nephrology, dialysis, transplantation : official…
BACKGROUND The renal response to ACE inhibition is known to vary between individuals. The ACE genotype is a determinant of the ACE concentrations in plasma and tissue, and therefore might affect the… Expand
Diagnostic value of dumping provocation in patients after gastric surgery.
- F. V. D. van der Kleij, J. Vecht, C. Lamers, A. A. Masclee
- Scandinavian journal of gastroenterology
- 1 December 1996
BACKGROUND In patients after gastric surgery it is often difficult to discern symptoms from dumping from other postcibal complaints. Strict criteria for dumping provocation test have not been… Expand