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MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling
Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer
Among lung cancer patients, CTC count significantly increased along with tumor progression, especially with development of distant metastasis, but a receiver operating characteristic (ROC) curve analysis showed an insufficient capability of the CTC test in discrimination between lung cancer and nonmalignant diseases.
Meta-analysis of postoperative adjuvant chemotherapy with tegafur-uracil in non-small-cell lung cancer.
It is shown that postoperative adjuvant chemotherapy with UFT was associated with improved 5- and 7-year survival in a Japanese patient population composed primarily of stage I adenocarcinoma patients.
Expression of angiopoietins and its clinical significance in non-small cell lung cancer.
Positive Ang-2 expression was significantly correlated with a poor prognosis, as well as with aggressive angiogenesis in resected NSCLC that was enhanced in the presence of high VEGF expression.
Evaluation of angiogenesis in non-small cell lung cancer: comparison between anti-CD34 antibody and anti-CD105 antibody.
- F. Tanaka, Y. Otake, H. Wada
- Biology, MedicineClinical cancer research : an official journal of…
- 1 November 2001
Anti-CD105 mAb proved to be superior to anti-CD34 mAb in evaluation of angiogenesis in NSCLC, and was a significant factor to predict poor prognosis.
Circulating tumor cells in pulmonary venous blood of primary lung cancer patients.
[18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung.
It is indicated that 18F-FDG uptake in lung cancer correlates well with the Glut-1, HK-II, and PCNA expression, and for nonmalignant lesions, the presence of a higher inflammatory process correlated with 18F, FDG uptake.
Matrix Metalloproteinase-2 Status in Stromal Fibroblasts, Not in Tumor Cells, Is a Significant Prognostic Factor in Non–Small-Cell Lung Cancer
MMP-2 status in stromal fibroblasts, not in tumor cells, was a significant prognostic factor associated with angiogenesis in NSCLC.
A Novel Classification of MUC1 Expression Is Correlated with Tumor Differentiation and Postoperative Prognosis in Non–Small Cell Lung Cancer
Frequent inactivation of the BAP1 gene in epithelioid‐type malignant mesothelioma
The results suggest that the lack of the tumor suppressor BAP1 may be more specifically involved in the pathogenesis of epithelioid MM rather than non‐epithelioids MM, and would be useful for diagnosis of epit helioid‐type MM.