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Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer
TLDR
Among lung cancer patients, CTC count significantly increased along with tumor progression, especially with development of distant metastasis, but a receiver operating characteristic (ROC) curve analysis showed an insufficient capability of the CTC test in discrimination between lung cancer and nonmalignant diseases.
Meta-analysis of postoperative adjuvant chemotherapy with tegafur-uracil in non-small-cell lung cancer.
TLDR
It is shown that postoperative adjuvant chemotherapy with UFT was associated with improved 5- and 7-year survival in a Japanese patient population composed primarily of stage I adenocarcinoma patients.
Expression of angiopoietins and its clinical significance in non-small cell lung cancer.
TLDR
Positive Ang-2 expression was significantly correlated with a poor prognosis, as well as with aggressive angiogenesis in resected NSCLC that was enhanced in the presence of high VEGF expression.
Evaluation of angiogenesis in non-small cell lung cancer: comparison between anti-CD34 antibody and anti-CD105 antibody.
  • F. Tanaka, Y. Otake, H. Wada
  • Biology, Medicine
    Clinical cancer research : an official journal of…
  • 1 November 2001
TLDR
Anti-CD105 mAb proved to be superior to anti-CD34 mAb in evaluation of angiogenesis in NSCLC, and was a significant factor to predict poor prognosis.
[18F]FDG uptake and PCNA, Glut-1, and Hexokinase-II expressions in cancers and inflammatory lesions of the lung.
TLDR
It is indicated that 18F-FDG uptake in lung cancer correlates well with the Glut-1, HK-II, and PCNA expression, and for nonmalignant lesions, the presence of a higher inflammatory process correlated with 18F, FDG uptake.
Matrix Metalloproteinase-2 Status in Stromal Fibroblasts, Not in Tumor Cells, Is a Significant Prognostic Factor in Non–Small-Cell Lung Cancer
TLDR
MMP-2 status in stromal fibroblasts, not in tumor cells, was a significant prognostic factor associated with angiogenesis in NSCLC.
Frequent inactivation of the BAP1 gene in epithelioid‐type malignant mesothelioma
TLDR
The results suggest that the lack of the tumor suppressor BAP1 may be more specifically involved in the pathogenesis of epithelioid MM rather than non‐epithelioids MM, and would be useful for diagnosis of epit helioid‐type MM.
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