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Learning from Nature: Pregnancy Changes the Expression of Inflammation-Related Genes in Patients with Multiple Sclerosis
Background Pregnancy is associated with reduced activity of multiple sclerosis (MS). However, the biological mechanisms underlying this pregnancy-related decrease in disease activity are poorlyExpand
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Normative Values for Intertrial Variability of Motor Responses to Nerve Root and Transcranial Stimulation: A Condition for Follow-Up Studies in Individual Subjects
Objective Intertrial variability (ITV) of motor responses to peripheral (CMAP) and transcranial (MEP) stimulation prevents their use in follow-up studies. Our purpose was to develop strategies toExpand
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No impact of current therapeutic strategies on disease reactivation after natalizumab discontinuation: a comparative analysis of different approaches during the first year of natalizumab
Natalizumab discontinuation induces the recurrence of multiple sclerosis disease activity: currently no therapeutic approach has been found able to abolish disease reactivation.
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High-Risk PML Patients Switching from Natalizumab to Alemtuzumab: an Observational Study
IntroductionThe choice of therapy in patients withdrawing from natalizumab treatment is still an open question and neurologists need strategies to manage this group of patients. The aim of this studyExpand
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The use of the 25 Sprotte needle markedly reduces post-dural puncture headache in routine neurological practice
Objectives The objectives of this article are to test the feasibility of lumbar puncture (LP) using 25-gauge (G) needles in daily neurological practice and to compare the risk of post-dural punctureExpand
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Treatment of multiple sclerosis with rituximab: A multicentric Italian-Swiss experience.
BACKGROUND Rituximab, an anti-CD20 monoclonal antibody leading to B lymphocyte depletion, is increasingly used as an off-label treatment option for multiple sclerosis (MS). OBJECTIVE To investigateExpand
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25G Sprotte Needle Strongly Reduces The Risk Of Post-Lumbare Puncture Headache In Clinical Practice. (P7.252)
OBJECTIVE: to evaluate the frequency of post-lumbar puncture headache (PLPH) using five types of needles. BACKGROUND: AAN guidelines (2005) suggest the use of 22G (gauge) atraumatic Sprotte needle;Expand
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Fingolimod is Not Able to Inhibit Multiple Sclerosis Disease Reactivation after Natalizumab Discontinuation (P7.206)
Objective: To study the effect of different therapeutic approach to inhibit the recurrence of disease activity after natalizumab discontinuation. Background: Natalizumab is a monoclonal antibody veryExpand
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High risk PML patients switching from natalizumab to alemtuzumab (P2.407)
Objective: Aim of this study is to evaluate the efficacy of alemtuzumab when used in patient who have stopped natalizumab. Background: The choice of therapy in patients withdrawing natalizumabExpand
A Low Percentage of CD4+ Cells Can Predict Disease Reactivation after Natalizumab Discontinuation (P2.063)
Objective: to evaluate whether lymphocytes sub-population could be related to MS disease reactivation at natalizumab suspension. Background: Natalizumab is a very effective second-line treatment forExpand