F. Socratous

Publications10
h-index9
Citations1,322
Highly Influential Citations41
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Sympathetic activation in chronic renal failure.
The potential involvement of sympathetic overactivity has been neglected in this population despite accumulating experimental and clinical evidence suggesting a crucial role of sympathetic activation… Expand
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Relation Between Cardiac Sympathetic Activity and Hypertensive Left Ventricular Hypertrophy
Background—Left ventricular (LV) hypertrophy is an independent risk factor for cardiovascular morbidity and mortality in hypertensive subjects. Sympathetic activation has been suggested to contribute… Expand
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Altered Sympathetic Nervous Reactivity and Norepinephrine Transporter Expression in Patients With Postural Tachycardia Syndrome
Background—Clinical observations in patients with postural tachycardia syndrome (POTS) suggest abnormal sympathetic nervous system activity and a dysfunction of the norepinephrine (NE) transporter… Expand
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Sympathetic Nerve Biology In Essential Hypertension
1. Although the importance of sympathetic nervous activation in the pathogenesis of essential hypertension is well documented, the exact pathophysiology of the sympathetic nervous dysfunction present… Expand
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The neuronal noradrenaline transporter, anxiety and cardiovascular disease
Panic disorder can serve as a clinical model for testing whether mental stress can cause heart disease. Potential neural mechanisms of cardiac risk are the sympathetic activation during panic… Expand
  • 68
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Renal denervation: a potential new treatment modality for polycystic ovary syndrome?
Objective Polycystic ovary syndrome (PCOS) is associated with sympathetic nervous system activation, insulin resistance, and blood pressure elevation. Renal nerve ablation has been demonstrated to… Expand
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Evidence for functional presynaptic alpha-2 adrenoceptors and their down-regulation in human heart failure.
OBJECTIVES The aim of this study was to investigate the role of peripheral presynaptic alpha-2 adrenergic receptors in modulating norepinephrine (NE) release in congestive heart failure (CHF). … Expand
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Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves
Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves
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Rilmenidine sympatholytic activity preserves mental stress, orthostatic sympathetic responses and adrenaline secretion
Background Heightened central sympathetic nervous outflow is common in essential hypertension, contributing to hypertension development and possibly also to complications. Acute sympathetic nervous… Expand
  • 35
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[Rilmenidine sympatholytic activity preserves mental and orthostatic sympathetic response and epinephrine secretion].
BACKGROUND Heightened central sympathetic nervous outflow is common in essential hypertension, contributing to hypertension development and perhaps also to complications. Acute sympathetic nervous… Expand
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  • 1