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Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term…
In this study, celecoxib, at dosages greater than those indicated clinically, was associated with a lower incidence of symptomatic ulcers and ulcer complications combined, as well as other clinically important toxic effects, compared with NSAIDs at standard dosages. Expand
Misoprostol Reduces Serious Gastrointestinal Complications in Patients with Rheumatoid Arthritis Receiving Nonsteroidal Anti-Inflammatory Drugs
This objective was to determine whether concurrent therapy with misoprostol reduces the incidence of serious upper gastrointestinal complications in older patients with chronic rheumatoid arthritis who are taking NSAIDs. Expand
Reduced risk of upper gastrointestinal ulcer complications with celecoxib, a novel COX-2 inhibitor
- J. Goldstein, F. Silverstein, +5 authors G. Geis
- American Journal of Gastroenterology
- 1 July 2000
The incidence of UGI ulcer complications associated with celecoxib was 8-fold lower than with nonspecific, nonsteroidal anti-inflammatory drugs (NSAIDs), and that in non-NSAID users reported in the literature was similar to that in patients receiving placebo in the RCTs. Expand
Transmission of Infection by Gastrointestinal Endoscopy and Bronchoscopy
The reported evidence of infections transmitted by flexible gastrointestinal and pulmonary endoscopes, the circumstances surrounding transmission of these infections, and recommended means to prevent such transmission are reviewed. Expand
The national ASGE survey on upper gastrointestinal bleeding. II. Clinical prognostic factors.
- F. Silverstein, D. Gilbert, F. Tedesco, N. Buenger, J. Persing
- Gastrointestinal endoscopy
- 1 May 1981
Although these results indicate a higher complication rate than earlier retrospective ASGE surveys on endoscopy, they are comparable to other available data about the risks of endoscopies in the specific group of patients with upper gastrointestinal bleeding. Expand
The national ASGE survey on upper gastrointestinal bleeding. III. Endoscopy in upper gastrointestinal bleeding.
The national ASGE survey on upper gastrointestinal bleeding. I. Study design and baseline data.
A reproducible animal model of acute bleeding ulcer-the "ulcer maker".
- R. Protell, F. Silverstein, J. Piercey, M. Dennis, W. Sprake, C. Rubin
- 1 December 1976
Using this ulcer model nonsurgical modalities for the treatment of upper gastrointestinal bleeding can be compared in a controlled manner and this standard experimental model may also facilitate comparison of results among different research groups. Expand
Double duct sign: reassessed significance in ERCP.
- T. Plumley, C. Rohrmann, P. Freeny, F. Silverstein, T. Ball
- AJR. American journal of roentgenology
Analysis of endoscopic retrograde cholangiopancreatography data indicates that the double duct sign per se is not disease specific, but when other ductal characteristics are assessed as a component of this finding, the ability to differentiate benign from malignant pancreatic disease is enhanced. Expand
Diagnosis of inflammatory bowel disease with ultrasound. An in vitro study.
- M. Kimmey, K. Wang, R. Haggitt, L. Mack, F. Silverstein
- Investigative radiology
- 1 October 1990
Ultrasound appears to be accurate in distinguishing normal from inflamed colon, but ultrasound findings alone should not be used to determine the cause of bowel inflammation. Expand