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Centrifugal and centripetal mechanisms involved in the 'gating' of cortical SEPs during movement.
Pre- and post-central cortical SEPs were of reduced amplitude and altered wave form when the median nerve stimulus was delivered during active movement of the thumb, suggesting that sensory input associated with the movement exerts a 'gating' effect which is at least as significant as that due to centrifugal influences.
Joubert syndrome: long-term follow-up.
Twenty-nine patients (16 males, 13 females) with Joubert syndrome were identified from ophthalmology, neurology, and genetic databases covering a 15-year period at Great Ormond Street Hospital,
Intermittent horizontal saccade failure ('ocular motor apraxia') in children.
Quick phase failure is a constant feature of OMA, whereas abnormal head movements were detected in only about half, depending on the underlying diagnosis, better described as an intermittent saccade failure rather than as a true apraxia.
Allelic variation of the FRMD7 gene in congenital idiopathic nystagmus.
It is demonstrated that phenotypic variation of nystagmus occurs in families with FRMD7 mutations, and the role of X inactivation in variable penetrance is unclear in congenital idiopathic nyStagmus.
Contribution of cutaneous and muscle afferent fibres to cortical SEPs following median and radial nerve stimulation in man.
Findings suggest that, contrary to an earlier report, muscle afferents do not make a major positive contribution to the scalp-recorded cortical responses produced by electrical stimulation of mixed nerves in the upper limb.
A comparison of flash electroretinograms recorded from Burian Allen, JET, C-glide, gold foil, DTL and skin electrodes
Single flash scotopic and photopic electroretinograms (ERGs) were recorded from the same subjects using six types of corneal electrode, in order to assess their relative effectiveness. In addition,
Common spectral domain OCT and electrophysiological findings in different pattern dystrophies
The degraded PERG results observed in this study indicate that the disease process in this condition is not limited to the RPE, and 3D-OCT features of reticular, multifocal and butterfly pattern dystrophies are reported.
Nystagmus in infancy.
A classification in which nyStagmus with an onset before 6 months is called early onset nystagmus (EON) and it is important to differentiate between SDN and CIN because of the different underlying defects, investigation, management, and genetic counselling.
Electrophysiological and eye-movement abnormalities in children with the Bardet-Biedl syndrome.
These results confirm other reports that the retinopathy appears to be a progressive rod-cone dystrophy initially affecting mainly extramacular areas but involving the macula at later stages.
Delayed visual maturation in infants: A disorder of figure—Ground separation?
It appears that infants with DVM are delayed in orienting to local regions of the visual field, but can respond to full-field motion, and the presence of normal pattern VEPs suggests a normal retino-geniculo-striate pathway.