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Alkaloids of Aconitum laeve and their anti-inflammatory antioxidant and tyrosinase inhibition activities.
The structure of compound 1 was deduced on the basis of spectral data and the anti-inflammatory, antioxidant and tyrosinase inhibition studies on all six compounds have also been carried out. Expand
Anticonvulsant Activities of the FS‐1 Subfraction Isolated from Roots of Delphinium denudatum
The results demonstrate the broad and potent anticonvulsant activity of the compounds in FS‐1 of D. denudatum, which significantly reduced mortality and delayed the onset of seizures. Expand
Isolation of Bioactive Compounds from Aspergillus terreus
A new metabolite, 6-(4’-hydroxy-2’-methyl phenoxy)-(-)-(3R)-mellein (1) was isolated from the ethyl acetate extract of Aspergillus terreus culture medium along with three known isocoumarinExpand
Microbial Transformation of Dehydroepiandrosterone
The structures of the transformation of dehydroepiandrosterone were determined by the spectroscopic techniques. Expand
Six new diterpenoids from Suregada multiflora.
Six new diterpenoids were isolated from a CH(2)Cl(2)-MeOH extract of the bark of Suregada multiflora on the basis of one- and two-dimensional NMR and other spectroscopic studies and chemical derivatizations. Expand
Three tyrosinase inhibitors and antioxidant compounds from Salsola foetida
Phytochemical investigation on the whole plant of Salsola foetida resulted in the isolation of three new phenolic compounds 1, 2, and 3, which exhibit tyrosinase inhibition with moderate antioxidantExpand
New cholinesterase inhibiting steroidal alkaloids from the leaves of Sarcococca coriacea of Nepalese origin.
From the leaves of Sarcococca coriacea two new steroidal alkaloids, epoxynepapakistamine-A and epoxysarcovagenine-D, were isolated and found to have cholinesterase inhibitory activity when tested for the inhibition of electric eel acetylcholiersterase and horse serum butyrylcholinestersterase. Expand
Anticonvulsant activities of ethanolic extract and aqueous fraction isolated from Delphinium denudatum.
The results suggest the presence of potent anticonvulsant compounds in AF of D. denudatum and deserve further investigation for isolation of active compounds and elucidation of the mechanism of anticonVulsant action. Expand
Biotransformation of (+)-androst-4-ene-3,17-dione
Five oxidative and reductive metabolites of androsta-1,4-diene-3,17-dione yielded microbially transformed products that were assayed against the clinically important enzymes, tyrosinase and prolyl endopeptidase. Expand
Microbial Transformation of (+)-Androsta-1,4-Diene-3,17-Dione by Cephalosporium Aphidicola
The fermentation of (+)-androsta-1,4-diene-3,17-dione with Cephalosporium aphidicola yielded oxidative and reductive metabolites and the structures of these metabolites were elucidated on the basis of spectroscopic techniques. Expand