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- Publications
- Influence
BRCA1 dysfunction in sporadic basal-like breast cancer
- N. Turner, J. Reis-Filho, +8 authors A. Tutt
- Biology, Medicine
- Oncogene
- 29 March 2007
Basal-like breast cancers form a distinct subtype of breast cancer characterized by the expression of markers expressed in normal basal/myoepithelial cells. Breast cancers arising in carriers of… Expand
Breast cancer prognostic classification in the molecular era: the role of histological grade
- E. Rakha, J. Reis-Filho, +15 authors I. Ellis
- Medicine
- Breast Cancer Research
- 30 July 2010
Breast cancer is a heterogeneous disease with varied morphological appearances, molecular features, behavior, and response to therapy. Current routine clinical management of breast cancer relies on… Expand
Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists
- S. Badve, D. Dabbs, +16 authors J. Reis-Filho
- Medicine
- Modern Pathology
- 1 February 2011
Breast cancer is a heterogeneous disease encompassing a variety of entities with distinct morphological features and clinical behaviors. Although morphology is often associated with the pattern of… Expand
A reciprocal tensin-3–cten switch mediates EGF-driven mammary cell migration
Cell migration driven by the epidermal growth factor receptor (EGFR) propels morphogenesis and involves reorganization of the actin cytoskeleton. Although de novo transcription precedes migration,… Expand
Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype
- S. Ricardo, A. F. Vieira, +6 authors J. Paredes
- Medicine, Biology
- Journal of Clinical Pathology
- 16 June 2011
Background and Aim The study of CD44/CD24 and ALDH1 expression is the most accurate method to identify cancer stem cells (CSC) from breast cancer populations. However, the overlap between… Expand
p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas
- I. Matos, R. Dufloth, M. Alvarenga, L. Zeferino, F. Schmitt
- Biology, Medicine
- Virchows Archiv
- 13 July 2005
Human breast carcinomas represent a heterogeneous group of tumors diverse in behavior, outcome, and response to therapy. However, the current system of pathological classification does not take into… Expand
P-cadherin expression in breast cancer: a review
- J. Paredes, A. L. Correia, A. S. Ribeiro, A. Albergaria, F. Milanezi, F. Schmitt
- Medicine
- Breast Cancer Research
- 31 October 2007
P-cadherin is frequently over-expressed in high-grade invasive breast carcinomas and has been reported to be an enhancer of migration and invasion of breast cancer cells, being correlated with tumour… Expand
Metaplastic breast carcinomas are basal‐like tumours
- J. Reis-Filho, F. Milanezi, +6 authors F. Schmitt
- Biology, Medicine
- Histopathology
- 1 July 2006
Aims : Recently, an immunohistochemical panel comprising antibodies against HER2, oestrogen receptor (ER), epidermal growth factor receptor (EGFR) and cytokeratin (CK) 5/6 was reported to identify… Expand
Phyllodes tumours of the breast: a consensus review
Phyllodes tumours constitute an uncommon but complex group of mammary fibroepithelial lesions. Accurate and reproducible grading of these tumours has long been challenging, owing to the need to… Expand
Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours
- A. Albergaria, J. Paredes, +9 authors F. Schmitt
- Medicine
- Breast Cancer Research
- 23 June 2009
IntroductionThe expression of additional genes, other than oestrogen receptor (ER), may be important to the hormone-responsive phenotype of breast cancer. Microarray analyses have revealed that… Expand