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Antimycobacterial constituents from Juniperus procera, Ferula communis and Plumbago zeylanica and their in vitro synergistic activity with isonicotinic acid hydrazide
The synergistic activity of antimycobacterial constituents from Saudi plants was evaluated in combination with isonicotinic acid hydrazide (INH) against four atypical organisms, namely, MycobacteriumExpand
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Selection and micropropagation of high artemisinin producing clones of Artemisia annua L.
An in vitro micropropagation method has been used to clone Artemisia annua L. plants from axenic seedlings or field grown plants selected on the basis of morphological characteristics during theExpand
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Artemisinin-derived sesquiterpene lactones as potential antitumour compounds: cytotoxic action against bone marrow and tumour cells.
We determined the in vitro cytotoxic activity of the sesquiterpene lactone endoperoxide artemisinin (1) and some chemically prepared derivatives, which have been found to display cytotoxicity toExpand
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Cytotoxic sesquiterpene lactones from Centaurothamnus maximus and Vicoa pentanema
The aerial parts of Centaurothamnus maximus yielded three cytotoxic guaianolides, chlorojanerin (1), cynaropicrin (2) and janerin (3). The structure elucidation of 1–3 was based on 1H and 13C NMRExpand
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Antiparasitic, nematicidal and antifouling constituents from Juniperus berries
A bioassay‐guided fractionation of Juniperus procera berries yielded antiparasitic, nematicidal and antifouling constituents, including a wide range of known abietane, pimarane and labdaneExpand
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Cell culture assay system for the evaluation of natural product-mediated anti-Hepatitis B virus activity.
Utilizing the hepatitis B virus (HBV)-producing hepatoblastoma cell line, HepG2.2.15, which is stably transfected with the cloned HBV genome, methods were devised to examine the effects of testExpand
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Clastogenic evaluation of cathinone and amphetamine in somatic cells of mice.
Clastogenic effects of cathinone, the active principle from khat (Catha edulis) and amphetamine, a compound having similar chemical structure and pharmacological activity, have been studied on theExpand
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Antioxidant effect of flavonoids on DCF production in HL‐60 cells
A fluorometric microplate assay was performed for the detection of respiratory burst activity in a human leukaemia cell line HL‐60 by assessing oxidation of 2′,7′‐dichlorofluorescin diacetateExpand
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New sesquiterpene lactones from Liriodendron tulipifera
Abstract Four new sesquiterpene lactones were obtained from L. tulipifera ; two germacranolides, lipiferolide ( 4 ) and epitulipinolide diepoxide ( 5 ) from the leaves, an elemanolide,Expand
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Labdane diterpenes from Otostegia fruticosa.
The new labdane diterpenes otostegin A (2), otostegin B (6) and 15-epi-otostegin B (7) were isolated from the aerial parts of Otostegia. fruticosa, besides the previously known labdanes preleoheterinExpand
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