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Cytochemical discrimination between catalases and peroxidases using diaminobenzidine
SummaryThe influence on diaminobenzidine staining of four variables: prefixation in aldehyde, temperature and pH of incubation, and H2O2 concentration, was investigated in catalase-, as well as inExpand
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A new peroxisomal disorder with enlarged peroxisomes and a specific deficiency of acyl-CoA oxidase (pseudo-neonatal adrenoleukodystrophy).
In the present paper two siblings are presented with clinical manifestations very similar to those of patients affected by neonatal adrenoleukodystrophy. In contrast to neonatal adrenoleukodystrophyExpand
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Evaluation of the preventive effect of glyceryl trioleate-trierucate ("Lorenzo's oil") therapy in X-linked adrenoleukodystrophy: results of two concurrent trials.
X-linked adrenoleukodystrophy (X-ALD) is characterized by progressive neurological disability and primary adrenocortical insufficiency as a consequence of mutations in the ABCD1 gene that encodes aExpand
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The Accessory Costotransverse Foramen: A Radioanatomical Study
One hundred fifty-six anatomical specimens of cervical vertebrae and 55 CI and 53 C2 vertebrae were examined for the presence of an accessory costotransverse foramen. We also reviewed 60 cervicalExpand
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Early effects of gentamicin, tobramycin, and amikacin on the human kidney.
The early alterations at the level of the proximal tubule of the human kidney caused by the three most currently used aminoglycosides, gentamicin, tobramycin, and amikacin, were studied. AExpand
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Pseudo-Zellweger syndrome: deficiencies in several peroxisomal oxidative activities.
We describe an infant girl with a clinical, chemical, and pathologic syndrome remarkably similar to Zellweger cerebrohepatorenal syndrome but whose liver parenchymal cells contained abundantExpand
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Liver plasma membrane: The source of high molecular weight alkaline phosphatase in human serum
This study presents biochemical, histochemical, morphological and immunological evidence that part of the high molecular weight alkaline phosphatase observed in the serum of patients with liverExpand
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Phenylbutyrate up-regulates the adrenoleukodystrophy-related gene as a nonclassical peroxisome proliferator
X-linked adrenoleukodystrophy (X-ALD) is a demyelinating disease due to mutations in the ABCD1 (ALD) gene, encoding a peroxisomal ATP-binding cassette transporter (ALDP). Overexpression ofExpand
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Mitochondrial Transmembrane Potential Changes Support the Concept of Mitochondrial Heterogeneity During Apoptosis
Dissipation of mitochondrial membrane potential (Δψm) and release of cytochrome c from mitochondria appear to be key events during apoptosis. The precise relationship (cause or consequence) betweenExpand
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Infantile Refsum disease: an inherited peroxisomal disorder
Three patients affected by infantile Refsum disease are described with mental retardation, minor facial dysmorphia, chorioretinopathy, sensorineural hearing deficit, hepatomegaly, failure to thriveExpand
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