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Bacterial iron homeostasis.
TLDR
The expression of the iron homeostatic machinery is subject to iron-dependent global control ensuring that iron acquisition, storage and consumption are geared to iron availability and that intracellular levels of free iron do not reach toxic levels. Expand
Global Iron-dependent Gene Regulation in Escherichia coli
TLDR
The macroarray-based global analysis of iron- and Fur-dependent gene expression in E. coli has revealed several novel Fur-repressed genes likely to specify at least three additional iron-transport pathways, providing compelling evidence for the regulation of intracellular iron consumption by the Fe2+-Fur complex. Expand
Two of the three groEL homologues in Rhizobium leguminosarum are dispensable for normal growth
TLDR
A detailed analysis of the requirement for and relative levels of these three proteins in the root-nodulating bacterium Rhizobium leguminosarum is reported, showing that only Cpn60.1 is required for growth of this organism. Expand
Induction of the ferritin gene (ftnA) of Escherichia coli by Fe2+–Fur is mediated by reversal of H‐NS silencing and is RyhB independent
TLDR
Results presented here show that ftnA iron induction is independent of RyhB and instead involves direct interaction of Fe2+–Fur with an ‘extended’ Fur binding site (containing five tandem Fur boxes) located upstream (−83) of the ftNA promoter. Expand
Expression of the nifBfdxNnifOQ region of Azotobacter vinelandii and its role in nitrogenase activity
TLDR
The NifQ(-)-producing mutation resulted in an increased (approximately 1,000-fold) Mo requirement for Mo nitrogenase activity, a phenotype already observed with Klebsiella pneumoniae; this is consistent with its very low expression under standard diazotrophic conditions. Expand
At least two nodD genes are necessary for efficient nodulation of alfalfa by Rhizobium meliloti.
A Rhizobium meliloti DNA region (nodD1) involved in the regulation of other early nodulation genes has been delimited by directed Tn5 mutagenesis and its nucleotide sequence has been determined. TheExpand
The R608del mutation in the acid sphingomyelinase gene (SMPD1) is the most prevalent among patients from Gran Canaria Island with Niemann‐Pick disease type B
TLDR
The R608del mutation was screened for in four pediatric patients from three unrelated families with the Niemann-Pick type B disease amongst patients from Northern Africa, and the presence of this mutation was confirmed by sequencing the deleted amplicon, for at least one member from each family. Expand
The influence of several variables for nitrosoguanidine mutagenesis inLactobacillus plantarum
TLDR
It was found that the optimal effects are achieved by exposing a suspension of about 109 log-phase cells to 500μg MNNG in 1 ml Tris-maleate buffer, for 30 min at 28°C in the dark and without shaking. Expand
The Bradyrhizobium japonicum nolA gene and its involvement in the genotype-specific nodulation of soybeans.
TLDR
A DNA region from B. japonicum strain USDA 110 which is involved in genotype-specific nodulation of soybeans is identified and sequenced and indicated that nolA was moderately induced by soybean seed extract and the isoflavone genistein, the regulator of mercury resistance genes. Expand
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