• Publications
  • Influence
The heritability of bipolar affective disorder and the genetic relationship to unipolar depression.
BACKGROUND Twin studies of bipolar affective disorder (BPD) have either been small or have not used explicit diagnostic criteria. There has been little use of genetic model fitting and no analyses toExpand
  • 990
  • 45
  • PDF
Analytic approaches to twin data using structural equation models
The classical twin study is the most popular design in behavioural genetics. Expand
  • 591
  • 28
  • PDF
Temporal and reciprocal relationship between IADL/ADL disability and depressive symptoms in late life.
A strong association between functional disability and depressive symptoms in older people has frequently been reported. Some studies attribute this association to the disabling effects ofExpand
  • 268
  • 18
Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample.
IMPORTANCE Most evidence to date highlights the importance of genetic influences on the liability to autism and related traits. However, most of these findings are derived from clinically ascertainedExpand
  • 270
  • 16
  • PDF
Heritability and Reliability of P300, P50 and Duration Mismatch Negativity
BackgroundEvent-related potentials (ERPs) have been suggested as possible endophenotypes of schizophrenia. We investigated the test–retest reliabilities and heritabilities of three ERP components inExpand
  • 166
  • 15
A twin study of genetic relationships between psychotic symptoms.
OBJECTIVE Biometrical model fitting was applied to clinical data from twins to investigate whether operationally defined schizophrenic, schizoaffective, and manic syndromes share genetic riskExpand
  • 432
  • 14
A quantitative genetic analysis of schizotypal personality traits
Background. Previous twin studies investigating the heritability of schizotypy have often had limited power and have failed to measure the disorganization/social anxiety component. Method. SevenExpand
  • 137
  • 14
An estimate of amyotrophic lateral sclerosis heritability using twin data
Background Causative gene mutations have been identified in about 2% of those with amyotrophic lateral sclerosis (ALS), often, but not always, when there is a strong family history. There is anExpand
  • 230
  • 13
  • PDF
Heritability of autism spectrum disorders: a meta‐analysis of twin studies
Background The etiology of Autism Spectrum Disorder (ASD) has been recently debated due to emerging findings on the importance of shared environmental influences. However, two recent twin studies doExpand
  • 361
  • 10
  • PDF
Etiology of different developmental trajectories of callous-unemotional traits.
OBJECTIVE To investigate the longitudinal development of callous-unemotional traits (CU) in middle childhood using developmental trajectory analyses in a large twin dataset and examine the degree toExpand
  • 156
  • 10