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Continuous-Flow Production of Injectable Liposomes via a Microfluidic Approach
Injectable liposomes are characterized by a suitable size and unique lipid mixtures, which require time-consuming and nonstraightforward production processes. The complexity of the manufacturingExpand
Use of in-die powder densification parameters in the implementation of process analytical technologies for tablet production on industrial scale.
The use of process analytical technologies (PAT) to ensure final product quality is by now a well established practice in pharmaceutical industry. To date, most of the efforts in this field haveExpand
Heating treatments affect the thermal behaviour of doxorubicin loaded in PEGylated liposomes.
Doxil® is a stealth marketed PEGylated liposomal formulation, containing the anticancer drug doxorubicin. After loading via a pH gradient, fibrillar supramolecular structures of doxorubicin sulfateExpand
A pharmaceutical composition comprising IL-6
Effect of the concentration process on unloaded and doxorubicin loaded liposomal dispersions
&NA; Liposomes are lamellar nanovesicles made of phospholipids of a great interest as drug delivery carriers, able to encapsulate both hydrophilic and lipophilic compounds. Some liposomalExpand
Continuous flow scalable production of injectable size-monodisperse nanoliposomes in easy-fabrication milli-fluidic reactors
Abstract The production of reproducible batches of liposomes suitable for parenteral administration is a time-consuming, multi-step process requiring extensive workable area. MicrofluidicExpand