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Chronic second‐by‐second measures of l‐glutamate in the central nervous system of freely moving rats
l‐glutamate (Glu) is the main excitatory neurotransmitter in the central nervous system (CNS) and is associated with motor behavior and sensory perception. While microdialysis methods have been usedExpand
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Microelectrode array studies of basal and potassium‐evoked release of l‐glutamate in the anesthetized rat brain
l‐glutamate (Glu) is the predominant excitatory neurotransmitter in the mammalian central nervous system. It plays major roles in normal neurophysiology and many brain disorders by binding toExpand
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Improved ceramic-based multisite microelectrode for rapid measurements of l-glutamate in the CNS
This paper describes improvements and further characterization of a ceramic-based multisite microelectrode for in vivo measurements of L-glutamate. Improvements include increased recording area,Expand
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Rapid microelectrode measurements and the origin and regulation of extracellular glutamate in rat prefrontal cortex
J. Neurochem. (2010) 115, 1608–1620.
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Second‐by‐second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats
These experiments utilized an enzyme‐based microelectrode selective for the second‐by‐second detection of extracellular glutamate to reveal the α7‐based nicotinic modulation of glutamate release inExpand
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Second-by-Second Measures of l-Glutamate in the Prefrontal Cortex and Striatum of Freely Moving Mice
l-Glutamate (Glu) is the main excitatory neurotransmitter in the mammalian central nervous system, and it is involved in most aspects of normal brain function, including cognition, memory andExpand
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Histological studies of the effects of chronic implantation of ceramic-based microelectrode arrays and microdialysis probes in rat prefrontal cortex
Chronic implantation of neurotransmitter measuring devices is essential for awake, behavioral studies occurring over multiple days. Little is known regarding the effects of long term implantation onExpand
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Dopamine Neuron Stimulating Actions of a GDNF Propeptide
Background Neurotrophic factors, such as glial cell line-derived neurotrophic factor (GDNF), have shown great promise for protection and restoration of damaged or dying dopamine neurons in animalExpand
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Diffuse brain injury elevates tonic glutamate levels and potassium-evoked glutamate release in discrete brain regions at two days post-injury: an enzyme-based microelectrode array study.
Traumatic brain injury (TBI) survivors often suffer from a wide range of post-traumatic deficits, including impairments in behavioral, cognitive, and motor function. Regulation of glutamate signalingExpand
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Ceramic-based multisite microelectrode arrays for simultaneous measures of choline and acetylcholine in CNS.
A ceramic-based microelectrode array (MEA) with enzyme coatings for the accurate measurement of acetylcholine (ACh) in brain tissues is presented. Novel design features allow for self-referencingExpand
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