• Publications
  • Influence
Intracellular localization and in vivo trafficking of p24A and p23.
TLDR
New insights are given into the localization and trafficking behavior of the two COPI-binding proteins p24A and p23, which are predominantly colocalized in the Golgi area. Expand
Depletion of Intracellular Calcium Stores Activates a Calcium Conducting Nonselective Cation Current in Mouse Pancreatic Acinar Cells*
TLDR
It is concluded that in mouse pancreatic acinar cells 40-45 pS nonselective cation channels serve as a pathway for capacitative Ca2+ entry, which differs from the previously described ICRAC in its ion-selectivity, pharmacological profile, and single-channel conductance. Expand
Histamine‐induced calcium entry in rat cerebellar astrocytes: evidence for capacitative and non‐capacitative mechanisms
TLDR
The results suggest that besides capacitative mechanisms, a non‐capacitative, voltage‐independent pathway is involved in histamine‐induced Ca2+ entry into cultured rat cerebellar astrocytes. Expand
Control of Ca2+ wave propagation in mouse pancreatic acinar cells.
TLDR
The data suggest that the slower propagation speed of bombesin-induced Ca2+ waves is due to higher activation of PKC in the presence ofBombesin compared with ACh, which could explain the slower propagate speed of Ca2+. Expand
Control of Ca2+ wave propagation in mouse pancreatic acinar cells.
TLDR
It is concluded that, following Ins(1,4,5) P 3-induced Ca2+ release in the luminal cell pole, secondary Ca 2+ release from stores, which are located in series between the luminals and the basal plasma membrane, modifies Ca2-spreading toward the basolateral cell side by Ca2+, which could explain the slower propagation of Ca2 + waves in the presence of bombesin compared with ACh. Expand
LOE 908 blocks delayed rectifier type potassium channels in PC12 cells and cortical neurons in culture.
TLDR
It is concluded that LOE 908 is a K+ channel blocker with selectivity for delayed outward rectifying K+ channels in undifferentiated cells and in rat cortical neurons in primary culture. Expand
Effect of intracellular pH on acetylcholine-induced Ca2+ waves in mouse pancreatic acinar cells.
TLDR
The data suggest that the propagation rate of ACh-induced Ca2+ waves is decreased by inhibition ofCa2+ release from intracellular stores due to cytosolic acidification or to Ca2- pool alkalinization and/or to a decrease in the proton gradient directed from the inositol 1,4,5-trisphosphate-sensitive Ca2+. Expand
Effect of intracellular pH on acetylcholine-induced Ca2+ waves in mouse pancreatic acinar cells.
TLDR
The data suggest that the propagation rate of ACh-induced Ca2+ waves is decreased by inhibition ofCa2+ release from intracellular stores due to cytosolic acidification or to Ca2- pool alkalinization and/or to a decrease in the proton gradient directed from the inositol 1,4, 5-trisphosphate-sensitive Ca2+. Expand
Control of Ca 2 1 wave propagation in mouse pancreatic acinar cells
Pfeiffer, Fatima, Lutz Sternfeld, Andreas Schmid, and Irene Schulz. Control of Ca21 wave propagation in mouse pancreatic acinar cells. Am. J. Physiol. 274 (Cell Physiol. 43): C663–C672, 1998.—We haveExpand
Capacitative Ca2+ influx and a Ca2u+-dependent nonselective cation pathway are discriminated by genistein in mouse pancreatic acinar cells
TLDR
It is concluded that this 28 pS nonselective cation channel does not contribute to Ca2+ influx into mouse exocrine pancreatic cells and the involvement of tyrosine phosphorylation in the activation of the Ca2- entry mechanism in mouse pancreatic acinar cells is unclear. Expand