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Clinical pharmacology and antiarrhythmic efficacy of N-acetylprocainamide.
Eleven patients with chronic ventricular arrhythmias took part in a study of N-acetylprocainamide (NAPA), the major metabolite of procainamide, in order to characterize further NAPA's clinicalExpand
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Serum Prolactin Levels in Patients With Fibrocystic Breast Disease
In 193 patients suffering from fibrocystic breast disease, basal serum prolactin concentrations were determined and compared to serum prolactin levels in 193 healthy women. In 45 additional patientsExpand
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Severity of Mastalgia in Relation to Milk Duct Dilatation
OBJECTIVE: The etiology of mastalgia is poorly understood. Histology cannot detect any distinct characteristics. This investigation therefore applied ultrasonography to mastalgia patients toExpand
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Thyrotrophin-releasing hormone--a lactation-promoting agent?
OBJECTIVE To study the lactational and hormonal responses to nasal administration of thyrotrophin-releasing hormone (TRH) in puerperal women with inadequate lactation. DESIGN Prospective randomizedExpand
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[Hand disinfection as the central factor in prevention of puerperal mastitis. Clinical study and results of a survey].
The incidence of puerperal mastitis was evaluated in the course of two 12-month periods with and without additional hand disinfection at the bedside. Disinfection was available throughout bothExpand
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Clinical electrophysiologic effects of encainide, a newly developed antiarrhythmic agent.
Encainide is a newly developed antiarrhythmic agent. With the use of intracardiac electrophysiologic techniques, its effects on the cardiac conduction system were examined in 10 patients withExpand
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Clinical Pharmacology and Antiarrhythmic Efficacy of Encainide in Patients with Chronic Ventricular Arrhythmias
We determined the pharmacokinetics, efficacy and therapeutic plasma concentration of encainide, a new antiarrhythmic drug that affects His-Purkinje conduction but not ventricular refractoriness. NineExpand
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Mechlorethamine HCl and cyclophosphamide in the treatment of Hodgkin's disease and the lymphomas.
Eighty-six patients (37 with Hodgkin's disease, 37 with lymphosarcoma, and 12 with reticulum cell sarcoma) were randomized and treated with either a single dose of mechlorethamine hydrochloride (0.4Expand
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Randomized double-blind placebo controlled crossover trial documenting oral lorcainide efficacy in suppression of symptomatic ventricular tachyarrhythmias.
Lorcainide, a new antiarrhythmic drug, was given to 10 patients with frequent (greater than 1/min) premature ventricular contractions (PVCs) on a baseline 24-hour Holter monitor. Each patientExpand
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Binding of human chorionic gonadotrophin to rat ovary during development.
Ovarian tissue of prenatal, newborn, and 5-day-old rats does not specifically bind 125I-labelled HCG. Specific binding of HCG was first observed in ovaries of 10-day-old animals and binding increasedExpand
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