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The locked-in syndrome : what is it like to be conscious but paralyzed and voiceless?
TLDR
There is an urgent need for a renewed ethical and medicolegal framework for the care of locked-in patients and patients suffering from LIS should not be denied the right to live - and to live with dignity and the best possible revalidation, and pain and symptom management. Expand
Locked-in syndrome in children: report of five cases and review of the literature.
TLDR
Findings raise important ethical considerations in terms of quality of life and end-of-life decisions in such challenging cases of pediatric locked-in syndrome patients. Expand
A survey on self-assessed well-being in a cohort of chronic locked-in syndrome patients: happy majority, miserable minority
TLDR
The self-reported quality of life in chronic LIS patients is studied to stress the need for extra palliative efforts directed at mobility and recreational activities in LIS and the importance of anxiolytic therapy. Expand
Cognitive function in the locked-in syndrome
TLDR
Results indicate that LIS patients can recover intact cognitive levels in cases of pure brainstem lesions, and that additional brain injuries are most likely responsible for associated cognitive deficits in the LIS. Expand
Life can be worth living in locked-in syndrome.
TLDR
New data on the psychosocial adjustment to locked-in syndrome are presented and the assumption among doctors, health-care workers, lay persons, and politicians that severe motor disability necessarily is intolerable and leads to end-of-life decisions or euthanasia is strongly questioned. Expand
Cognitive Processing in Non-Communicative Patients: What Can Event-Related Potentials Tell Us?
TLDR
It is concluded that, in spite of keeping full consciousness and intact or nearly intact cortical functions, LIS patients present less reliable results when testing with ERP, specifically in the passive condition, and strongly recommend applying ERP paradigms in an active condition when evaluating consciousness in non-responsive patients. Expand
Serotoninergic, noradrenergic, and peptidergic innervation of Onuf's nucleus of normal and transected spinal cords of baboons (papio papio)
TLDR
It is found that serotoninergic innervation has two origins: first, supraspinal, innervating the whole nucleus, with a possible predominance in the dorsal half; and second, intraspINAL, corresponding to the ventral half of the nucleus. Expand
Le locked-in syndrome
TLDR
Les premières descriptions d’état apparenté au LIS semblent provenir de la littérature de l’aide de clignements de paupières and de mouvements verticaux. Expand
Beyond the gaze: Communicating in chronic locked-in syndrome
TLDR
The results highlight the possibility to recover non-eye dependent communication, speech production and some functional movement in the majority of chronic LIS patients. Expand
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