Written action plan in pediatric emergency room improves asthma prescribing, adherence, and control.
- F. Ducharme, R. Zemek, Xun Zhang
- MedicineAmerican Journal of Respiratory and Critical Care…
- 15 January 2011
RATIONALE An acute-care visit for asthma often signals a management failure. Although a written action plan is effective when combined with self-management education and regular medical review, its…
Preemptive use of high-dose fluticasone for virus-induced wheezing in young children.
In preschool-age children with moderate-to-severe virus-induced wheezing, preemptive treatment with high-dose fluticasone as compared with placebo reduced the use of rescue oral corticosteroids.
Conditionally Activated E7 Proteins of High-Risk and Low-Risk Human Papillomaviruses Induce S Phase in Postmitotic, Differentiated Human Keratinocytes
- N. S. Banerjee, Nicholas Genovese, F. Noya, W. Chien, T. R. Broker, L. Chow
- BiologyJournal of Virology
- 1 July 2006
It is proved unequivocally that the E7 protein drives S-phase reentry in postmitotic, differentiated keratinocytes rather than preventing S- phase exit while the cells ascend through the epithelium, entirely consistent with the fact that low-risk HPV genotypes replicate in the differentiated strata in patient specimens, as do the high-risk HPVs.
Human Papillomavirus E6E7-Mediated Adenovirus Cell Killing: Selectivity of Mutant Adenovirus Replication in Organotypic Cultures of Human Keratinocytes
ABSTRACT Replication-competent adenoviruses are being investigated as potential anticancer agents. Exclusive virus replication in cancer cells has been proposed as a safety trait to be considered in…
Humoral immunity 10 years after booster immunization with an adolescent and adult formulation combined tetanus, diphtheria, and 5-component acellular pertussis vaccine.
Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors
- F. Ducharme, F. Noya, F. Allen-Ramey, E. Maiese, Joanie Gingras, L. Blais
- MedicineCurrent Medical Research and Opinion
- 1 January 2012
The prescription of ICS monotherapy did not significantly reduce rescue oral corticosteroids or acute care visits and was associated with a higher rate of hospital admission for asthma and rescue β2-agonist use.
Transduction of the E6 and E7 genes of epidermodysplasia-verruciformis-associated human papillomaviruses alters human keratinocyte growth and differentiation in organotypic cultures.
- I. Boxman, L. Mulder, J. ter Schegget
- Biology, MedicineThe Journal of investigative dermatology
- 1 December 2001
In organotypic cultures, when the E6 and E7 genes of epidermodysplasia-verruciformis-associated human papilloma virus types 15 and 17 were transduced, a broadening layer of basal cells and an accelerated differentiation were observed, and "papilla-like structures" comprising basal-like keratinocytes arose from the basal layer into the differentiated layers.
Comparison of the safety and immunogenicity of concomitant and sequential administration of an adult formulation tetanus and diphtheria toxoids adsorbed combined with acellular pertussis (Tdap)…
CSACI position statement: systemic effect of inhaled corticosteroids on adrenal suppression in the management of pediatric asthma
- K. Issa-El-Khoury, Harold Kim, E. Chan, T. V. Vander Leek, F. Noya
- MedicineAllergy, Asthma & Clinical Immunology
- 14 March 2015
The Canadian Society of Allergy and Clinical Immunology (CSACI) recommends that physicians screen for adrenal suppression in children receiving high doses for more than 6 months and to consider screening those on medium dose if the risk is deemed higher by factors that increase an individual's systemic corticosteroid exposure.
The Promoter of the Human Proliferating Cell Nuclear Antigen Gene Is Not Sufficient for Cell Cycle-dependent Regulation in Organotypic Cultures of Keratinocytes*
It is demonstrated that E7 reactivated the transcription of the endogenous hPCNA in differentiated keratinocytes, and the native pattern of expression largely restored, indicative of the complexity of its regulation.