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Written action plan in pediatric emergency room improves asthma prescribing, adherence, and control.
RATIONALE An acute-care visit for asthma often signals a management failure. Although a written action plan is effective when combined with self-management education and regular medical review, itsExpand
Preemptive use of high-dose fluticasone for virus-induced wheezing in young children.
TLDR
In preschool-age children with moderate-to-severe virus-induced wheezing, preemptive treatment with high-dose fluticasone as compared with placebo reduced the use of rescue oral corticosteroids. Expand
Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors
TLDR
The prescription of ICS monotherapy did not significantly reduce rescue oral corticosteroids or acute care visits and was associated with a higher rate of hospital admission for asthma and rescue β2-agonist use. Expand
Comparison of the safety and immunogenicity of concomitant and sequential administration of an adult formulation tetanus and diphtheria toxoids adsorbed combined with acellular pertussis (Tdap)
TLDR
While there is a small diminution in antibody response to tetanus and pertussis antigens, concomitant administration of Tdap and influenza vaccine was well tolerated and immunogenic and may offer practical advantages including convenience, compliance, and cost- savings. Expand
Humoral immunity 10 years after booster immunization with an adolescent and adult formulation combined tetanus, diphtheria, and 5-component acellular pertussis vaccine.
Persistence of antibodies after a single dose of Tdap vaccine (tetanus, diphtheria, and 5-component acellular pertussis vaccine) was evaluated in a follow-up study of adolescents (N=324) and adultsExpand
Disposition of an immunoglobulin intravenous preparation in very low birth weight neonates.
TLDR
Assessment of potential efficacy of IGIV in the prevention of late-onset infection in VLBW neonates finds that the infusion of this product was well tolerated and changes in hemoglobin, hematocrit, and total hemolytic complement occurred as expected. Expand
FOXP3 forkhead domain mutation and regulatory T cells in the IPEX syndrome.
TLDR
To the Editor: The immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome, a rare disorder characterized by multiorgan autoimmunity, often results in death in infancy, and identification of the functional consequences of individual mutations is critical. Expand
Humoral immunity 5 years after booster immunization with an adolescent and adult formulation combined tetanus, diphtheria, and 5-component acellular pertussis vaccine.
TLDR
Humoral immune responses to all antigens were robust 1 month after initial immunization; antibodies exceeded pre-immunization levels 1, 3, and 5 years later, contributing to selecting the optimal interval for booster doses of Tdap. Expand
The Asthma Quiz for Kidz: a validated tool to appreciate the level of asthma control in children.
TLDR
The Asthma Quiz score provides complementary information to, but does not replace, lung function testing and should prompt patients to consult their physician for reassessment. Expand
Group a streptococcus spinal epidural abscess during varicella.
TLDR
2 children, ages 18 months and 5 years, who were admitted recently to 2 pediatric hospitals in Montreal with a resolving varicella, abdominal and lumbar pain, and a refusal to walk are described, in whom a diagnosis of epidural abscess caused by group A streptococcus (GAS) was established. Expand
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