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- Publications
- Influence
Post-mitotic human dermal fibroblasts efficiently support the growth of human follicular keratinocytes.
- A. Limat, T. Hunziker, C. Boillat, K. Bayreuther, F. Noser
- Biology, Medicine
- The Journal of investigative dermatology
- 1 May 1989
For growth at low seeding densities, keratinocytes isolated from human tissues like epidermis or hair follicles are dependent on mesenchyme-derived feeder cells such as the 3T3-cell employed so far.… Expand
Serial cultivation of single keratinocytes from the outer root sheath of human scalp hair follicles.
A method for the isolation of outer root sheath keratinocytes from plucked human hair follicles and for their subsequent cultivation has been developed. The selective trypsinization of outer root… Expand
Restoration of the epidermal phenotype by follicular outer root sheath cells in recombinant culture with dermal fibroblasts.
- A. Limat, D. Breitkreutz, +5 authors N. Fusenig
- Biology, Medicine
- Experimental cell research
- 1 June 1991
In order to better understand how outer root sheath (ORS) cells are able to reepithelialize superficial skin wounds, the level of epidermal differentiation achieved by isolated ORS cells in vitro was… Expand
Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells
- A. Limat, D. Breitkreutz, +4 authors N. Fusenig
- Chemistry, Medicine
- Annals of the New York Academy of Sciences
- 1 December 1991
Follicles of human anagen hair were separated into morphologically distinct compartments (by sequential trypsinization and microdissection) for the biochemical and immunological analysis of keratins… Expand
Studies on the potential in vivo induction of sister-chromatid exchanges in rat bone marrow by resorcinol.
- M. Bracher, J. Świstak, F. Noser
- Biology, Medicine
- Mutation research
- 1 July 1981
The hair-dye component resorcinol was tested for potential in vivo induction of sister-chromatid exchanges (SCE) in bone-marrow cells after intraperitoneal, peroral and epicutaneous application to… Expand
Outer root sheath (ORS) cells organize into epidermoid cyst-like spheroids when cultured inside Matrigel: a light-microscopic and immunohistological comparison between human ORS cells and…
- A. Limat, D. Breitkreutz, +4 authors L. Braathen
- Biology, Medicine
- Cell and Tissue Research
- 2004
In organotypic cultures, outer root sheath (ORS) cells of the human hair follicle develop into a stratified epithelium largely reminiscent of the epidermis; this apparently reflects their importance… Expand
Organotypic culture of outer root sheath cells from human hair follicles using a new culture device
SummaryA new culture vessel for the growth of cells on biological substrata and under organotypic conditions is described. This device, named Combi-ring-dish (CRD), is composed of four concentric… Expand
Differentiation and polypeptide expression in human papilla and dermal fibroblasts in vitro.
- P. I. Francz, K. Bayreuther, A. Limat, F. Noser
- Biology, Medicine
- European journal of cell biology
- 1 April 1993
Proliferation and differentiation of human scalp hair follicle papilla fibroblasts (PF) in the anagenic stage of development and of neighboring dermal fibroblasts (DF) of the same donor were studied… Expand
Postmitotic human dermal fibroblasts preserve intact feeder properties for epithelial cell growth after long-term cryopreservation
- A. Limat, T. Hunziker, C. Boillat, F. Noser, U. Wiesmann
- Biology, Medicine
- In Vitro Cellular & Developmental Biology
- 1 July 1990
SummaryIn vitro, human dermal fibroblasts (HDF) differentiate through morphologically and biochemically identified compartments. In the course of this spontaneous differentiation through mitotic and… Expand
Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo.
- A. Limat, D. Breitkreutz, +4 authors N. Fusenig
- Biology, Medicine
- Epithelial cell biology
- 1 April 1993
Trichocytes, i.e. precursor cells of the hair cortex and medulla, isolated from plucked human scalp hair follicles (HF) were propagated on feeder layers of post-mitotic human dermal fibroblasts… Expand