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YC-1, a novel activator of platelet guanylate cyclase.
YC-1 [3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole] inhibited the aggregation of and ATP release from washed rabbit platelets induced by arachidonic acid (AA), collagen, U46619, platelet-activatingExpand
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YC‐1 inhibited human platelet aggregation through NO‐independent activation of soluble guanylate cyclase
1 Our previous study demonstrated that YC‐1, a derivative of benzylindazole, is a novel activator of soluble guanylate cyclase (sGC) in rabbit platelets. This work investigated whether theExpand
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Antioxidant properties of butein isolated from Dalbergia odorifera.
The antioxidant properties of butein, isolated from Dalbergia odorifera T. Chen, were investigated in this study. Butein inhibited iron-induced lipid peroxidation in rat brain homogenate in aExpand
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Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat.
The mitogenic effect of activated coagulation factor X (factor Xa) was examined in cultured aortic smooth muscle cells (VSMC) from Wistar-Kyoto rats (WKY). Factor Xa stimulated DNA synthesis and cellExpand
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Bioactive constitutents from the stems of Annona montana.
Three structurally related acid amides, N-trans-feruloyltyramine (1), N-p-coumaroyltyramine (2), and N-trans-caffeoyltyramine (3), one lignan, (-)-syringaresinol (4), one aromatic aldehyde,Expand
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Two antiplatelet agents from Magnolia officinalis.
Magnolol and honokiol are two position isomers isolated from the bark of Magnolia officinalis. Both inhibited the aggregation and ATP release of rabbit platelet-rich plasma induced by collagen andExpand
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Vasorelaxation of rat thoracic aorta caused by osthole isolated from Angelica pubescens.
The pharmacological effects of osthole on isolated rat thoracic aorta were examined. Osthole inhibited norepinephrine (NE, 3 microM)-induced phasic and tonic contractions in rat thoracic aorta in aExpand
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Coumarins and antiplatelet aggregation constituents from Formosan Peucedanum japonicum.
Four new khellactone esters, (-)-trans-3'-acetyl-4'-senecioylkhellactone, (+-)-cis-3'-acetyl-4'-tigloylkhellactone, (+-)-cis-4-tigloylkhellactone, (+)-trans-4'-tigloylkhellactone, together with 14Expand
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Antiplatelet Effect of Gingerol Isolated from Zingiber officinale
The purpose of this investigation was to determine the antiplatelet mechanism of gingerol.
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Coumarins and anti-platelet aggregation constituents from Zanthoxylum schinifolium.
Six new coumarins, schinicoumarin, acetoxyaurapten, epoxycollinin, schininallylol, schinilenol and schinindiol, along with seven known coumarins, aurapten, collinin, epoxyaurapten, hydrangetin,Expand
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