• Publications
  • Influence
POST‐INJURY MULTIPLE ORGAN FAILURE: THE ROLE OF THE GUT
ABSTRACT— Despite intensive investigation, the pathogenesis of post‐injury multiple organ failure (MOF) remains elusive. Laboratory and clinical research strongly suggests that the gastrointestinalExpand
  • 456
  • 13
Intra-abdominal vagal blocking (VBLOC therapy): clinical results with a new implantable medical device.
BACKGROUND A new medical device uses high-frequency electrical algorithms to create intermittent vagal blocking (VBLOC therapy). The aim is to assess the effects of vagal blocking on excess weightExpand
  • 153
  • 6
The role of the gut in the development of sepsis in acute pancreatitis.
The pathogenesis of sepsis in acute pancreatitis is unknown. Since the intestinal tract has recently been identified as a possible source for sepsis in other conditions, we explored whether the gutExpand
  • 216
  • 5
Selection of electrical algorithms to treat obesity with intermittent vagal block using an implantable medical device.
BACKGROUND A laparoscopically implantable electrical device that intermittently blocks both vagi near the esophagogastric junction led to significant excess weight loss (EWL) in an initial clinicalExpand
  • 55
  • 5
Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults.
Inducible nitric oxide synthase (NOS 2) is thought to play a role in gut motility disorders that occur under proinflammatory conditions. Clinically, ileus occurs after sepsis and shock-induced gutExpand
  • 82
  • 4
[Diseases of the liver and biliary tract].
The authors intend this book to be "streamlined to the needs of the clinician," as suggested in the preface. Indeed, at a time when texts of hepatology are becoming heavier and multivolumed, thisExpand
  • 117
  • 3
  • PDF
Dramatic reversal of derangements in muscle metabolism and left ventricular function after bariatric surgery.
OBJECTIVE The study objective was to define muscle metabolic and cardiovascular changes after surgical intervention in clinically severe obese patients. METHODS Obesity is a state of metabolicExpand
  • 81
  • 3
Decreased ileal muscle contractility and increased NOS II expression induced by lipopolysaccharide.
This study was designed to determine if an increase in nitric oxide synthase (NOS) activity induced by lipopolysaccharide (LPS) is associated with increases in NOS II protein and mRNA abundance andExpand
  • 71
  • 2
Body weight, insulin resistance, and serum adipokine levels 2 years after 2 types of bariatric surgery.
OBJECTIVE Bariatric surgery reverses obesity-related comorbidities, including type 2 diabetes mellitus. Several studies have already described differences in anthropometrics and body composition inExpand
  • 83
  • 2
Stress ulcers: their pathogenesis, diagnosis, and treatment.
Stress ulcers are multiple, superficial erosions which occur mainly in the fundus and body of the stomach. They develop after shock, sepsis, and trauma and are ofter found in patients withExpand
  • 39
  • 2