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Effect of rare variants in ADRB2 on risk of severe exacerbations and symptom control during longacting β agonist treatment in a multiethnic asthma population: a genetic study.
BACKGROUND Severe adverse life-threatening events associated with longacting β agonist (LABA) use have caused the US Food and Drug Administration (FDA) to review the safety of these drugs, resultingExpand
Comparative prevalence of sensitization to common animal, plant and mould allergens in subjects with asthma, or atopic dermatitis and/or allergic rhinitis living in a tropical environment
Background and objectives Current information suggests that the expression of allergic diseases is determined by the exposure and nature of the allergen. The objectives of the present study were toExpand
Identification of the domestic mite fauna of Puerto Rico.
This study was conducted to identify the domestic mite fauna of Puerto Rico. A total of 57 dust samples were collected from mattresses in homes of 11 cities on the Island. The analysis of the samplesExpand
Issues and methods in disparities research: The Rhode Island–Puerto Rico asthma center
Epidemiologic studies have documented higher rates of asthma prevalence and morbidity in minority children compared to non‐Latino white (NLW) children. Few studies focus on the mechanisms involved inExpand
Sensitization to Blomia tropicalis in patients with asthma and identification of allergen Blo t 5.
In tropical and subtropical regions of the world, allergens produced by Blomia tropicalis are an important cause of IgE-mediated sensitization among patients with asthma. We compared the relativeExpand
Detection of serine proteases in extracts of the domestic mite Blomia tropicalis
Previous studies have shown that the domestic mites Dermatophagoides pteronyssinus and D. farinae contain allergens with serine protease activity. These proteolytic allergens include trypsin,Expand
Correlative Clinical Biochemistry and Hematological Profiles of Laboratory‐Bred Bolivian Squirrel Monkeys (Saimiri sciureus)
Twenty‐five clinical and biochemical parameters were determined on 17 normal, male, laboratory‐bred Bolivian squirrel monkeys (Saimiri sciureus). Parallel hematologic parameters were conducted. TheExpand
Growth inhibition of Babesia bovis in culture by secretions from bovine mononuclear phagocytes.
Bovine blood mononuclear phagocytes from babesia-free cattle were cultured in vitro. Cell monolayers were treated with culture-derived soluble Babesia bovis exoantigens, immune complexes, and bovineExpand
Cloning and expression of Blo t 1, a novel allergen from the dust mite Blomia tropicalis, homologous to cysteine proteases
Background House dust mite allergens have been shown to be a very important stimulus in the causation of asthma and triggers for the exacerbation of symptoms. Therefore, characterization ofExpand
Prevalence of skin reactions to aeroallergens in asthmatics of Puerto Rico.
In Puerto Rico, although a high prevalence of asthma has been reported, the sensitization rates to aeroallergens in these patients is unknown. The purpose of this study using a case control design,Expand