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Hypertaurinuria in the C57BL/6J mouse: altered transport at the renal basolateral membrane.
The C57BL/6J mouse is an inbred strain with selective hypertaurinuria. C3H/HeJ mice (control) and C57BL/6J mice have comparable values for plasma taurine and renal creatinine clearance butExpand
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A -aminobutyrate pathway in mammalian kidney cortex.
Abstract Rat kidney cortex converts l -glutamate to γ-aminobutyrate by a decarboxylation reaction which differs from the corresponding reaction in brain. Renal l -glutamate decarboxylase has twoExpand
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Amino acid transport in mammalian kidney: Multiple systems for imino acids and glycine in rat kidney.
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The ontogeny of amino acid transport in rat kidney. II. Kinetics of uptake and effect of anoxia.
Abstract Low -K m transport of l -proline and glycine and high -K m transport of α-aminoisobutyric acid is absent in newborn Long-Evans rat kidney cortex slices. Other modes of uptake found in matureExpand
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Transport and metabolism of sarcosine in hypersarcosinemic and normal phenotypes.
An adolescent male proband with hypersarcosinemia was discovered incidentally in a French-Canadian family; no specific disease was associated with the trait. The hypersarcosinemia is not diminishedExpand
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Glutamic Acid Decarboxylase and Gamma-aminobutyric Acid in Mammalian Kidney
THE discovery of glutamic acid decarboxylase (GAD) in mammalian brain was first reported in 19501,2. The product of this enzyme reaction is gamma-aminobutyric acid (GABA), an importantExpand
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Abstract 1. More than one mode of transport can be observed for concentrative uptake of α-aminoisobutyric acid (AIB) by rat kidney cortex slices when the initial concentration of AIB in the medium isExpand
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A microassay for analysis of serum sulfate.
Abstract A simple assay for analysis of sulfate in a 100-μl volume of serum is described. Selective precipitation of 133Ba after removal of protein with trichloroacetic acid is reproducible andExpand
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The ontogeny of amino acid transport in rat kidney. I. Effect on distribution ratios and intracellular metabolism of proline and glycine.
Abstract Newborn Long-Evans rat pups have reduced tubular reabsorption of proline, hydroxyproline and glycine in vivo. Reabsorption of iminoacids improves one week after birth; glycine transportExpand
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