F. Mohd Jaafar

Publications27
h-index16
Citations1,108
Highly Influential Citations77
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Common evolutionary origin of aquareoviruses and orthoreoviruses revealed by genome characterization of Golden shiner reovirus, Grass carp reovirus, Striped bass reovirus and golden ide reovirus…
TLDR
Genetic analysis revealed homology in the genes of the aquareovirus and orthoreoviruses groups, indicating clear genetic relatedness between members of distinct genera, unique within the family Reoviridae.
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Detection of a Fourth Orbivirus Non-Structural Protein
TLDR
Bioinformatic analyses indicate that NS4 contains coiled-coils, is related to proteins that bind nucleic acids, or are associated with membranes and shows similarities to nucleolar protein UTP20 (a processome subunit).
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Genus Coltivirus (family Reoviridae): genomic and morphologic characterization of Old World and New World viruses
TLDR
These findings, together with the comparative analysis to genomes of south-east Asian isolates, support the recent classification of arboviruses with 12 segments of dsRNA within two distinct genera and raise interesting questions about the evolutionary origins of coltiviruses.
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Yunnan orbivirus, a new orbivirus species isolated from Culex tritaeniorhynchus mosquitoes in China.
TLDR
The replication of YUOV in mosquito cell lines was restricted to Aedes albopictus cells and the virus failed to replicate in mammalian cell lines, however, intraperitoneal injection of virus into naïve mice resulted in productive, non-lethal virus replication and viraemia.
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Complete characterisation of the American grass carp reovirus genome (genus Aquareovirus: family Reoviridae) reveals an evolutionary link between aquareoviruses and coltiviruses.
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Expansion of family Reoviridae to include nine-segmented dsRNA viruses: isolation and characterization of a new virus designated Aedes pseudoscutellaris reovirus assigned to a proposed genus…
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Isolation and full-length sequence analysis of Armigeres subalbatus totivirus, the first totivirus isolate from mosquitoes representing a proposed novel genus (Artivirus) of the family Totiviridae.
TLDR
Based on a recent reassessment of the coding strategy used by IMNV, it is suggested that an AsTV coat-RdRp fusion protein could be synthesized via a -1 frameshift.
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Liao ning virus, a new Chinese seadornavirus that replicates in transformed and embryonic mammalian cells.
TLDR
LNV is the first reported seadornavirus that replicates in mammalian cells, leading to massive cytopathic effect in all transformed or embryonic cell lines tested, and was identified as a member of a new species of virus.
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Complete sequence of Great Island virus and comparison with the T2 and outer-capsid proteins of Kemerovo, Lipovnik and Tribec viruses (genus Orbivirus, family Reoviridae).
TLDR
Phylogenetic analyses of the RNA-dependent RNA polymerase (Pol) and T2 protein amino acid sequences indicated that the tick-borne orbiviruses represent an ancestral group from which the mosquito-borne Orbivirus species have evolved, supporting a co-speciation hypothesis for these arboviruses and their arthropod-vectors.
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Complete nucleotide sequence of Middelburg virus, isolated from the spleen of a horse with severe clinical disease in Zimbabwe.
TLDR
The first full-length sequence of MIDV, which was obtained from a single RT-PCR product, is reported, which is similar to that of other alphaviruses.
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