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Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.
Tuberous Sclerosis Complex (TSC) is a multisystem genetic disorder characterized by hamartomatous neurological lesions that exhibit abnormal cell proliferation and differentiation. Hyperactivation of… Expand
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients
Adenosine Deaminase (ADA) deficiency is an autosomal recessive variant of severe combined immunodeficiency (SCID) caused by systemic accumulation of ADA substrates. Neurological and behavioral… Expand
Chromosome 20 Ring: A Chromosomal Disorder Associated with a Particular Electroclinical Pattern
Summary: Purpose: The chromosome 20 ring [r(20)] is a rare chromosomal disorder without clear phenotypical markers. We describe the electroclinical pattern in a group of patients with r(20).
Treatment of Status Epilepticus in Adults: Guidelines of the Italian League Against Epilepsy
- F. Minicucci, G. Muscas, E. Perucca, G. Capovilla, F. Vigevano, P. Tinuper
- 1 December 2006
Summary: Status epilepticus (SE) is a medical emergency which can lead to significant morbidity and mortality and requires prompt diagnosis and treatment. SE is differentiated into generalized or… Expand
Effects of incretin treatment on cardiovascular outcomes in diabetic STEMI-patients with culprit obstructive and multivessel non obstructive-coronary-stenosis
- R. Marfella, C. Sardu, +11 authors M. Barbieri
- Diabetology & Metabolic Syndrome
- 3 January 2018
BackgroundNo proper data on prognosis and management of type-2 diabetic ST elevation myocardial infarction (STEMI) patients with culprit obstructive lesion and multivessel non obstructive coronary… Expand
Quantitative EEG and LORETA: valuable tools in discerning FTD from AD?
- F. Caso, M. Cursi, G. Magnani, G. Fanelli, F. Minicucci
- Medicine, Psychology
- Neurobiology of Aging
- 1 October 2012
Drawing a clinical distinction between frontotemporal dementia (FTD) and Alzheimer's disease (AD) is tricky, particularly at the early stages of disease. This study evaluates the possibility in… Expand
Treatment of convulsive status epilepticus in childhood: Recommendations of the Italian League Against Epilepsy
- G. Capovilla, F. Beccaria, E. Beghi, F. Minicucci, S. Sartori, M. Vecchi
- 1 October 2013
The Italian League Against Epilepsy Commission Guidelines Subcommittee on Status Epilepticus (SE) has published an article on the management of SE in adults, and now presents a report on the… Expand
Effects of Metformin Therapy on Coronary Endothelial Dysfunction in Patients With Prediabetes With Stable Angina and Nonobstructive Coronary Artery Stenosis: The CODYCE Multicenter Prospective Study
OBJECTIVE To evaluate the effect of metformin therapy on coronary endothelial function and major adverse cardiac events (MACE) in patients with prediabetes with stable angina and nonobstructive… Expand
Non‐ST‐elevation myocardial infarction outcomes in patients with type 2 diabetes with non‐obstructive coronary artery stenosis: Effects of incretin treatment
There are insufficient data on the prognosis and management of people with type 2 diabetes who experience a non‐obstructive coronary artery stenosis (NOCS)–non‐ST‐elevation myocardial infarction… Expand
High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt…
BackgroundNeurotoxicity is a recognized complication of cyclosporine A (CSA) treatment. The incidence of severe CSA-related neurological complications following hematopoietic stem cell… Expand