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- Publications
- Influence
Placebos without Deception: A Randomized Controlled Trial in Irritable Bowel Syndrome
- T. Kaptchuk, E. Friedlander, +7 authors A. Lembo
- Medicine
- PloS one
- 22 December 2010
Background Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception. We tested whether open-label… Expand
The ethics of placebo-controlled trials--a middle ground.
- E. Emanuel, F. Miller
- Medicine
- The New England journal of medicine
- 2001
HE first placebo-controlled trial was probably conducted in 1931, when sanocrysin was compared with distilled water for the treatment of tuberculosis. 1 Ever since then, placebo-controlled trials… Expand
Placebo Effects in Medicine.
- T. Kaptchuk, F. Miller
- Medicine
- The New England journal of medicine
- 1 July 2015
Research has revealed placebo effects to be genuine biopsychosocial phenomena representing more than simply spontaneous remission or normal symptom fluctuations. How can this understanding be used to… Expand
Communicating the Results of Clinical Research to Participants: Attitudes, Practices, and Future Directions
- David I. Shalowitz, F. Miller
- Medicine
- PLoS medicine
- 1 May 2008
The authors discuss the available data on the effects of communicating aggregate and individual research results on participants, investigators, and the research enterprise.
The therapeutic orientation to clinical trials.
- F. Miller, D. Rosenstein
- Medicine
- The New England journal of medicine
- 3 April 2003
Traditionally, clinical trials have been understood as continuous with clinical medicine.1 In providing medical care for patients, the physician makes observations, investigates, tests hypotheses, ...
Clinical Trials and Medical Care: Defining the Therapeutic Misconception
- G. Henderson, L. Churchill, +13 authors C. Zimmer
- Medicine
- PLoS medicine
- 1 November 2007
A key component of informed consent to participate in medical research includes understanding that research is not the same as treatment.
The Nocebo Effect and Its Relevance for Clinical Practice
- L. Colloca, F. Miller
- Psychology, Medicine
- Psychosomatic medicine
- 23 August 2011
Negative expectations deriving from the clinical encounter can produce negative outcomes, known as nocebo effects. Specifically, research on the nocebo effect indicates that information disclosure… Expand
The Placebo Effect: Illness and Interpersonal Healing
- F. Miller, F. G. L. Colloca, Franklin G. Luana Ted J. Kaptchuk
- Medicine
- Perspectives in biology and medicine
- 2009
The placebo effect has been a source of fascination, irritation, and confusion within biomedicine over the past 60 years. Although scientific investigation has accelerated in the past decade, with… Expand
Disclosing individual results of clinical research: implications of respect for participants.
- David I. Shalowitz, F. Miller
- Medicine
- JAMA
- 10 August 2005
What Makes Placebo-Controlled Trials Unethical?
The leading ethical position on placebo-controlled clinical trials is that whenever proven effective treatment exists for a given condition, it is unethical to test a new treatment for that condition… Expand