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Serum fragment of cytokeratin subunit 19 measured by CYFRA 21-1 immunoradiometric assay as a marker of lung cancer.
Cytokeratin 19 is a subunit of cytokeratin intermediate filament expressed in simple epithelia and their malignant counterparts. Therefore, it is expressed by respiratory epithelium cells and hasExpand
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Quality of life in asthma. I. Internal consistency and validity of the SF-36 questionnaire.
Asthma is a chronic disease in which social life is altered. The importance of restrictions on social life may be greater in severe asthma or when symptoms are not adequately controlled. GeneralExpand
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Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease.
BACKGROUND Eosinophils but not neutrophils may play a role in the airway inflammation of asthma. In chronic bronchitis (CB) and chronic obstructive pulmonary disease (COPD), neutrophils are presentExpand
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Chest radiography and high resolution computed tomography of the lungs in asthma.
CT scans have been studied only in asthmatics who were smokers, and no such study has been performed in patients with chronic uncomplicated asthma where a permanent bronchial destruction is likely toExpand
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Correlation between symptoms and the threshold for release of mediators in nasal secretions during nasal challenge with grass-pollen grains.
Nasal challenges with pollen grains represent one of the techniques of provocation. However, the clinical criteria of positivity are not clearly established. Nasal challenges with increasing numbersExpand
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Allergy in the Mediterranean area I. Pollen counts and pollinosis of Montpellier
The climatic conditions of the Mediterranean area results in vegetation and pollen very different from that of the other parts of Europe. The pollen content of the atmosphere of Montpellier, southernExpand
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Comparison of cord blood immunoglobulin E concentrations and maternal allergy for the prediction of atopic diseases in infancy.
Total serum IgE levels were determined in 136 newborns and their mothers and in 54 of their fathers, using the paper radioimmunosorbent test (PRIST) technique. IgE specific antibodies for house dustExpand
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Placebo-controlled double-blind food challenge in asthma.
To determine the prevalence of food allergy as a cause of exacerbation of asthma, we studied 300 consecutive patients with asthma (7 months to 80 years of age) who attended a respiratory clinic. EachExpand
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Immunotherapy with a standardized Dermatophagoides pteronyssinus extract. Systemic reactions during the rush protocol in patients suffering from asthma.
Specific immunotherapy can induce severe systemic reactions (SRs), especially in patients with asthma. It also appears that potent standardized extracts may be more often involved in the generationExpand
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HLA-DR and ICAM-1 expression on bronchial epithelial cells in asthma and chronic bronchitis.
HLA-DR and ICAM-I molecules play an important role in cellular interactions, and their expression can be induced by inflammatory stimuli. We evaluated the spontaneous expression of HLA-DR and ICAM-1Expand
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