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The prevalence, patterns and impact of irritable bowel syndrome: an international survey of 40 000 subjects
- A. Hungin, P. Whorwell, J. Tack, F. Mearín
- Alimentary pharmacology & therapeutics
- 1 March 2003
Aim : To determine the prevalence, symptom pattern and impact of the irritable bowel syndrome, across eight European countries, using a standardized methodology.
Functional Bowel Disorders
Employing a consensus approach, our working team critically considered the available evidence and multinational expert criticism, revised the Rome II diagnostic criteria for the functional bowel… Expand
Dyspepsia and irritable bowel syndrome after a Salmonella gastroenteritis outbreak: one-year follow-up cohort study.
BACKGROUND & AIMS It has been reported that some patients develop functional digestive disorders, particularly irritable bowel syndrome (IBS), after acute gastroenteritis (AGE). However, the presence… Expand
Patients with achalasia lack nitric oxide synthase in the gastro‐oesophageal junction
- F. Mearín, M. Mourelle, +4 authors J. Malagelada
- Biology, Medicine
- European journal of clinical investigation
- 1 November 1993
Abstract. The abnormal function of the lower oesophageal sphincter in achalasia is likely to be due to impaired nonadrenergic, noncholinergic (NANC) inhibitory input. Since recent studies in animals… Expand
The origin of symptoms on the brain-gut axis in functional dyspepsia.
It was hypothesized that symptoms in functional dyspepsia are originated by an altered mechanism at the brain-gut axis (one or several) in the process of gastric accommodation to a meal. To test the… Expand
Pyloric dysfunction in diabetics with recurrent nausea and vomiting.
Diabetes mellitus has been associated with a variety of gastrointestinal motor disturbances. Pyloric activity, however, has not been specifically investigated. We have quantified the pyloric… Expand
Severity in Irritable Bowel Syndrome: A Rome Foundation Working Team Report
- D. Drossman, L. Chang, +5 authors P. Whorwell
- The American Journal of Gastroenterology
- 1 October 2011
OBJECTIVES:The concept of severity in irritable bowel syndrome (IBS) is clinically recognized and operative in diagnostic decision making and treatment planning. Yet, there is no consensus on its… Expand
Irritable bowel syndrome prevalence varies enormously depending on the employed diagnostic criteria: comparison of Rome II versus previous criteria in a general population.
BACKGROUND Irritable bowel syndrome (IBS) prevalence estimates are essential for measuring the importance of the problem and the burden of the illness. However, IBS diagnosis is based on clinical… Expand
Gastric tone determines the sensitivity of the stomach to distention.
- R. Notivol, B. Coffin, F. Azpiroz, F. Mearín, J. Serra, J. Malagelada
- 1 February 1995
BACKGROUND/AIMS Whether meal-related symptoms such as postcibal epigastric fullness and discomfort are caused by hypotonic gastric expansion or gastric hypertension is unknown. This study… Expand
One year intermittent rifaximin plus fibre supplementation vs. fibre supplementation alone to prevent diverticulitis recurrence: a proof-of-concept study.
- Á. Lanas, J. Ponce, A. Bignamini, F. Mearín
- Digestive and liver disease : official journal of…
- 1 February 2013
BACKGROUND Evidence supporting appropriate medical therapy to prevent recurrence of colonic diverticulitis is limited. Our goal was to evaluate the potential of rifaximin given periodically in… Expand