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Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins.
The peptide sequence information for each member of the putative seven-protein complex previously described for Acanthamoeba and human platelets is obtained and a conserved and dynamic role for this complex in the organization of the actin cytoskeleton is proposed. Expand
The pharmacokinetics of midazolam in paediatric patients
- K. Payne, F. Mattheyse, D. Liebenberg, T. Dawes
- European Journal of Clinical Pharmacology
A serum concentration profile study on midazolam in children was done and the oral route bioavailability halved to 15% at the two higher doses, while the intramuscular and rectal routes had 87%, 18%, 27% respectively at a dose of 0.15 mg·kg−1. Expand
Dietary and hormonal regulation of urea cycle enzymes in rat liver.
When 6-week-old rats fed normal diet (22% protein) were transferred to 10 and 75% protein diet, the levels of urea cycle enzymes showed decreases and increases respectively. The activities expressed… Expand
Behavioural changes in children following minor surgery--is premedication beneficial?
Only for night-time crying and day-time toilet training did age below five years prove to be a significant contributing factor, and overall, premedication showed little benefit. Expand
Oral midazolam in paediatric premedication.
- K. Payne, A. Coetzee, F. Mattheyse, T. Dawes
- South African medical journal = Suid-Afrikaanse…
- 6 April 1991
Oral midazolam, intramuscularly and orally, produced more satisfactory behaviour than the other two regimens and, combined with a 70% more rapid recovery than the TMD regimen, suggests that oral midrazolam is a more effective paediatric premedication agent than placebo or TMD. Expand
Reduced Activation of Peripheral Blood Neutrophils after Late-Phase Asthmatic Responses but Not in Mild Stable Asthma
During episodes of asthmatic airway obstruction, in the laboratory and in clinical disease, neutrophil activation decreased in PB, conceivably because activated cells may be preferentially sequestered in the lung. Expand
Outcome of pregnancy in the morbidly obese woman
Morbidly obese women experienced increased complications during pregnancy and childbirth, and the main outcomes to be determined were ante-, intra- and postpartum maternal complications, rate of epidurals, and perinatal outcomes. Expand
The effect of thyroxine and hypertonic environment on the enzymes of the urea cycle in Xenopus laevis.
- J. B. Balinsky, T. Coetzer, F. Mattheyse
- Biology, Medicine
- Comparative biochemistry and physiology. B…
- 15 September 1972
There is no evidence that activation of a macromolecular precursor of the enzyme plays any role in elevating the level of carbamoylphosphate synthesase under these conditions. Expand
Midazolam and amnesia in pediatric premedication.
One hundred and twenty-eight children aged three to ten years, were studied to determine the effect of premedication on amnesia for the preanesthetic period and the potential advantages of amnesia in pediatric premedications are discussed. Expand
An organ culture of postnatal rat liver slices
A technique for the organ culture of postnatal and adult rat liver has been developed and orotate was shown to be spread over the entire slice of neonatal liver, and induction of urea cycle enzymes by cortisol was demonstrated in cultures of liver from adrenalectomized adult animals. Expand