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mtDNA mutations increase tumorigenicity in prostate cancer.
Mutations in the mtDNA have been found to fulfill all of the criteria expected for pathogenic mutations causing prostate cancer. Focusing on the cytochrome oxidase subunit I (COI) gene, we found thatExpand
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Expression profiling of renal epithelial neoplasms: a method for tumor classification and discovery of diagnostic molecular markers.
The expression patterns of 7075 genes were analyzed in four conventional (clear cell) renal cell carcinomas (RCC), one chromophobe RCC, and two oncocytomas using cDNA microarrays. Expression profilesExpand
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The tuberous sclerosis complex and its highly variable manifestations.
PURPOSE Tuberous sclerosis is an autosomal dominant neurocutaneous syndrome affecting multiple organ systems and demonstrating highly variable clinical manifestations. Mutations in 2 tumor suppressorExpand
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The management of renal angiomyolipoma.
Revue des cas de la litterature mondiale et de 13 cas personnels. Un schema therapeutique systematique est propose base a la fois sur la taille de la tumeur et les symptomes
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Induction of immunity to prostate cancer antigens: results of a clinical trial of vaccination with irradiated autologous prostate tumor cells engineered to secrete granulocyte-macrophage
Vaccination with irradiated granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting gene-transduced cancer vaccines induces tumoricidal immune responses. In a Phase I human gene therapyExpand
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XMRV infection in patients with prostate cancer: novel serologic assay and correlation with PCR and FISH.
OBJECTIVES To develop a serum-based assay to detect neutralizing antibodies to the xenotropic murine leukemia virus-related virus (XMRV) retrovirus and to use this assay with polymerase chainExpand
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In vivo molecular and cellular imaging with quantum dots.
Quantum dots (QDs), tiny light-emitting particles on the nanometer scale, are emerging as a new class of fluorescent probe for in vivo biomolecular and cellular imaging. In comparison with organicExpand
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Molecular classification of renal tumors by gene expression profiling.
Renal tumor classification is important because histopathological subtypes are associated with distinct clinical behavior. However, diagnosis is difficult because tumor subtypes have overlappingExpand
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Anomalies of the inferior vena cava and renal veins: embryologic and surgical considerations.
Anomalies of the inferior vena cava and renal veins occur infrequently but if unidentified can lead to significant morbidity during surgical exploration. An understanding of the embryologicExpand
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Laparoscopic radical nephrectomy: cancer control for renal cell carcinoma.
PURPOSE We evaluated the clinical efficacy of laparoscopic versus open radical nephrectomy in patients with clinically localized renal cell carcinoma. MATERIALS AND METHODS Between 1991 and 1999,Expand
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