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High-performance liquid chromatographic preparation of galactosyl-hydroxylysine, a specific bone collagen marker.
Galactosyl-hydroxylysine, a specific bone collagen marker, has been prepared directly from human urine samples by high-performance liquid chromatography (HPLC) on a preparative column. The compound… Expand
Urinary β-1-galactosyl-0-hydroxylysine (GH) as a marker of collagen turnover of bone
- L. Moro, R. S. Mucelli, C. Gazzarrini, C. Modricky, F. Marotti, B. Bernard
- Chemistry, Medicine
- Calcified Tissue International
- 1 February 1988
Measurement of GH in urine provides a simple and noninvasive method for the evaluation of the extent of bone resorption in large groups of subjects and appears to be more specific than urinary hydroxyproline excretion. Expand