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Association of Toll-like receptor 4 gene polymorphisms with normal tension glaucoma.
PURPOSE Toll-like receptor 4 (TLR4) is a transmembrane receptor that mediates immune responses to exogenous and endogenous ligands and interacts with heat shock proteins, which are reportedlyExpand
The association between Japanese primary open-angle glaucoma and normal tension glaucoma patients and the optineurin gene
Glaucoma represents one of the most common eye diseases and is characterized by progressive loss of visual fields. In the more advanced stages bilateral blindness may result, due to optic nerveExpand
Common Variants on Chromosome 9p21 Are Associated with Normal Tension Glaucoma
Although intraocular pressure (IOP) is the most definitive cause of glaucoma, a subtype of open angle glaucoma (OAG) termed normal tension glaucoma (NTG), which occurs in spite of normal IOP,Expand
Lysyl oxidase-like 1 gene polymorphisms in Japanese patients with primary open angle glaucoma and exfoliation syndrome
Purpose To assess whether lysyl oxidase-like 1 (LOXL1) polymorphisms are associated with primary open-angle glaucoma (POAG) and exfoliation syndrome (XFS). Methods Japanese patients with POAG (n=213)Expand
High Prevalence of Anxiety and Depression in Patients With Primary Open-angle Glaucoma
PurposeTo assess anxiety and depression in patients with primary open-angle glaucoma (POAG). DesignMulticenter prospective case-control study. ParticipantsTwo hundred thirty patients with POAG andExpand
ASSOCIATION OF LOC387715 A69S GENOTYPE WITH VISUAL PROGNOSIS AFTER PHOTODYNAMIC THERAPY FOR POLYPOIDAL CHOROIDAL VASCULOPATHY
Purpose: To investigate whether there is an association of the LOC387715 A69S genotype with visual prognosis after photodynamic therapy in eyes with polypoidal choroidal vasculopathy (PCV). Methods:Expand
Association between genetic variants associated with vertical cup-to-disc ratio and phenotypic features of primary open-angle glaucoma.
PURPOSE To assess the association between the genetic variants associated with the optic nerve vertical cup-to-disc ratio (VCDR) and the phenotypic features in patients with primary open-angleExpand
Association between SRBD1 and ELOVL5 gene polymorphisms and primary open-angle glaucoma.
PURPOSE The S1 RNA binding domain 1 (SRBD1) and elongation of long-chain fatty acids family member 5 (ELOVL5) have been reported to be susceptibility genes for early-onset normal-tension glaucomaExpand
The OPA1 gene polymorphism is associated with normal tension and high tension glaucoma.
PURPOSE To assess whether genetic polymorphisms of optic atrophy 1 (OPA1) are associated with primary open-angle glaucoma (POAG). DESIGN Prospective case control association study. METHODSExpand
Risk factors for anxiety and depression in patients with glaucoma
Aim To assess the risk factors for anxiety and depression in patients with glaucoma. Methods Anxiety and depression in 408 patients with glaucoma were evaluated using the hospital anxiety andExpand
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