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The immunomodulatory activity of human umbilical cord blood‐derived mesenchymal stem cells in vitro
Bone marrow‐derived mesenchymal stem cells (BM‐MSC) are currently being investigated in preclinical and clinical settings because of their self‐renewal and multipotent differentiative capacity or… Expand
Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21
Long noncoding RNAs (lncRNAs) are aberrantly expressed in various cancers. Although lncRNA GAS5 (growth arrest-specific transcript 5) has been characterized as a tumor suppressor in some kinds of… Expand
Metatranscriptome of an Anaerobic Benzene-Degrading, Nitrate-Reducing Enrichment Culture Reveals Involvement of Carboxylation in Benzene Ring Activation
- F. Luo, Roya Gitiafroz, +4 authors E. Edwards
- Biology, Medicine
- Applied and Environmental Microbiology
- 2 May 2014
ABSTRACT The enzymes involved in the initial steps of anaerobic benzene catabolism are not known. To try to elucidate this critical step, a metatranscriptomic analysis was conducted to compare the… Expand
Effects of pulsed electromagnetic field frequencies on the osteogenic differentiation of human mesenchymal stem cells.
The purpose of this study was to evaluate the effect of different frequencies of pulsed electromagnetic fields on the osteogenic differentiation of human mesenchymal stem cells. Third-generation… Expand
STAT3-regulated exosomal miR-21 promotes angiogenesis and is involved in neoplastic processes of transformed human bronchial epithelial cells.
Although microRNA (miRNA) enclosed in exosomes can mediate intercellular communication, the roles of exosomal miRNA and angiogenesis in lung cancer remain unclear. We investigated functions of… Expand
MicroRNA‐191, by promoting the EMT and increasing CSC‐like properties, is involved in neoplastic and metastatic properties of transformed human bronchial epithelial cells
Lung cancer is the leading cause of cancer mortality worldwide. A common interest in lung cancer research is the identification of biomarkers for early diagnosis and accurate prognosis. There is… Expand
The lncRNA MALAT1, acting through HIF-1α stabilization, enhances arsenite-induced glycolysis in human hepatic L-02 cells.
Accelerated glycolysis, a common process in tumor cells called the Warburg effect, is associated with various biological phenomena. However, the role of glycolysis induced by arsenite, a… Expand
A MALAT1/HIF-2α feedback loop contributes to arsenite carcinogenesis
Arsenic is well established as a human carcinogen, but the molecular mechanisms leading to arsenic-induced carcinogenesis are complex and elusive. It is also not known if lncRNAs are involved in… Expand
Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and…
Intercellular communication between malignant cells and neighboring nonmalignant cells is involved in carcinogenesis. In the progression of carcinogenesis, exosomes are messengers for intercellular… Expand
Occurrence of emerging organic contaminants in a tropical urban catchment in Singapore.
- Yonglan Xu, F. Luo, Amrita Pal, K. Gin, M. Reinhard
- Environmental Science, Medicine
- 1 May 2011
Emerging organic contaminants (EOCs) occurring in urban runoff can negatively impact sensitive ecosystems and drinking water resources. The occurrence of 13 EOCs was characterized in the Marina… Expand