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Effects of pulsed electromagnetic field frequencies on the osteogenic differentiation of human mesenchymal stem cells.
TLDR
P pulsed electromagnetic field frequency of 50 Hz was the most effective at inducing human mesenchymal stem cell osteoblast differentiation in vitro.
Umbilical cord Wharton's Jelly: a new potential cell source of mesenchymal stromal cells for bone tissue engineering.
TLDR
Bone morphogenetic protein 2 (BMP2)-induced osteogenic differentiation and activation of signaling pathways in UCMSCs and BMSCs showed a phenotype and differentiation potential similar to that of B MSCs, which would support the use ofUCMSCs in TEB.
Induction of granulation tissue for the secretion of growth factors and the promotion of bone defect repair
TLDR
The matured induced membrane and periosteum had similar structures and abilities to promote the osteogenesis of mesenchymal stem cells and secreted growth factors to promote osteogenesis.
MicroRNA-24 inhibits osteosarcoma cell proliferation both in vitro and in vivo by targeting LPAATβ.
TLDR
It is indicated that miR-24 is reduced in osteosarcoma cells, contributing to up-regulation of LPAATβ and resultant osteosARcoma cell proliferation.
Induced membrane technique for the treatment of bone defects due to post-traumatic osteomyelitis
TLDR
The induced membrane technique for the treatment of post-traumatic osteomyelitis is a simple, reliable method, with good early results, however, there are many challenges in determining the scope of the debridement, type of limb fixation and source of bone graft to be used.
Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway
TLDR
DHA is protective against LPS-induced bone loss through apoptosis induction of osteoclasts via ROS accumulation and the mitochondria-dependent apoptosis pathway, indicating that DHA may be considered as a new therapeutic candidate for treating inflammatory bone loss.
The outcomes of chemotherapy only treatment on mild spinal tuberculosis
TLDR
It is believed that the mild spinal TB respond well to the standard chemotherapy, and the detailed description of mild TB would provide crucial guidance in determination of conservative treatment.
Involvement of Toll-Like Receptor 2 and Pro-Apoptotic Signaling Pathways in Bone Remodeling in Osteomyelitis
TLDR
It is shown that osteoblast apoptosis and osteogenic differentiation in response to bacterial invasion are dependent on TLR2 expression and JNK activation, suggesting novel potential therapeutic targets for the treatment of osteomyelitis.
Bone marrow enriched graft, modified by self-assembly peptide, repairs critically-sized femur defects in goats
TLDR
NAP modified demineralized bone matrix (DBM) provided a more effective osteogenesis and regeneration for critically-sized femur defects in goats using the selective cell retention (SCR) strategy.
Changing expression profiles of lncRNAs, mRNAs, circRNAs and miRNAs during osteoclastogenesis
TLDR
A systematic perspective on the potential function of non-coding RNAs (ncRNAs) during osteoclastogenesis is provided and co-expression networks of lncRNA-mRNA and circRNA-miRNA were constructed based on the correlation analysis between the differentially expressed RNAs.
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