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Erectile dysfunction in male heroin users, receiving methadone and buprenorphine maintenance treatment.
TLDR
Both psychological and social factors were associated with ED, which is an important problem for many males in methadone and buprenorphine treatment, while living with a sexual partner was associated with a lower likelihood of ED, while depression, having aSexual partner with a history of drug use and not having a steady partner wereassociated with a greater likelihood ofED. Expand
Tobacco Addiction and Smoking Status in Heroin Addicts under Methadone vs. Buprenorphine Therapy
TLDR
The high prevalence of smokers among heroin addicts, the highest described in the literature to date amongHeroin addicts under substitution therapies, is confirmed, without any significant difference between methadone vs. buprenorphine therapy groups. Expand
Treatment of Benzodiazepine Dependence.
TLDR
Concerns are raised about the not using the PainDETECT score at recruitment and thus potentially including participants who may not have neuropathic pain features and therefore an indication for pregabalin, and the decision not to provide physical therapy to all participants. Expand
Patients in long-term maintenance therapy for drug use in Italy: analysis of some parameters of social integration and serological status for infectious diseases in a cohort of 1091 patients
TLDR
A significant percentage of heroin users in treatment for opiate addiction in the cohort study have characteristics which indicate reasonable integration within broader society, and it is posit that the combination of effective treatment and a setting of economic prosperity may enhance the social integration of patients with a history of heroin use. Expand
Compliance with hepatitis B vaccination in 1175 heroin users and risk factors associated with lack of vaccine response.
TLDR
A large-scale, multi-site hepatitis B vaccination programme for heroin users proved feasible and effective and the factors associated with a lack of antibody response may be useful in identifying patients who would benefit most from routine post-vaccination testing. Expand
High dose benzodiazepine dependence: Description of 29 patients treated with flumazenil infusion and stabilised with clonazepam
TLDR
A case series of benzodiazepine detoxification by flumazenil infusion, stabilised with clonazepam is presented, finding that more than two-thirds of the subjects tolerated the procedure well and about half had a good long term response. Expand
Cigarette Smoking Blocks the Protective Expression of Nrf2/ARE Pathway in Peripheral Mononuclear Cells of Young Heavy Smokers Favouring Inflammation
TLDR
Cigarette smoke promotes oxPAPC formation and oxidative stress in PBMC that may cause the activation of NF-kB that in turn may participate in the negative regulation of Nrf2/ARE pathway favouring inflammation. Expand
Study of 2708 heroin-related deaths in north-eastern Italy 1985-98 to establish the main causes of death.
TLDR
To be female and to have dropped out of any kind of treatment proved an important risk factor for overdose, and the fall in deaths from AIDS enhances the problem to prevent and treat HCV infection. Expand
Determinants of Quality of Life in High-Dose Benzodiazepine Misusers
TLDR
Physical and psychological dimensions of QoL are significantly lower in high-dose BZD misusers with no significant effect of comorbidities, and the data suggest that the main reason for poor quality of life (QoL) in these patients is high- dose BZd intake per se. Expand
Factors associated with hepatitis C virus infection in injection and noninjection drug users in Italy.
TLDR
The prevalence of hepatitis C virus (HCV) infection among noninjection users of heroin in Italy and among long-term NIDUs, however, it appeared to plateau at approximately 40%, and additional research is needed to develop a strategic prevention program for this patient subgroup. Expand
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