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Major lower extremity amputation: outcome of a modern series.
HYPOTHESIS Major lower extremity amputation results in significant morbidity and mortality. DESIGN Retrospective database query and medical record review for January 1, 1990, to December 31, 2001.Expand
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Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes.
Abnormalities in vascular reactivity in the micro- and macrocirculation are well established in type 2 diabetes. However, little is known about changes in vascular reactivity in those at risk forExpand
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A decade of experience with dorsalis pedis artery bypass: analysis of outcome in more than 1000 cases.
OBJECTIVE The purpose of this study was to review our experience over the last decade with the dorsalis pedis bypass for ischemic limb salvage in patients with diabetes mellitus. METHODS The studyExpand
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The high risk foot in diabetes mellitus
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Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration.
We studied endothelial-mediated microvascular blood flow in neuropathic diabetic patients to determine the association between endothelial regulation of the microcirculation and the expression ofExpand
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Endothelium-dependent vasodilatation is impaired in both microcirculation and macrocirculation during acute hyperglycemia.
PURPOSE Endothelial dysfunction is associated with atheromatosis and is a common finding with diabetes. We have studied the effects of acute hyperglycemia on the endothelium-dependent vasodilatationExpand
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A decade experience with infrainguinal revascularization in a dialysis-dependent patient population.
OBJECTIVE Although previous series have reported outcomes of lower extremity (LE) revascularization in patients with end-stage renal disease, the issue of LE bypass for limb salvage in this group hasExpand
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Soluble intercellular adhesion molecule, vascular cell adhesion molecule, and impaired microvascular reactivity are early markers of vasculopathy in type 2 diabetic individuals without
OBJECTIVE Using von Willebrand Factor (vWF) as a marker of endothelial function, previous studies have shown that the development of microalbuminuria is associated with the onset of endothelialExpand
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Differences in Foot and Forearm Skin Microcirculation in Diabetic Patients With and Without Neuropathy
OBJECTIVE We have compared the hyperemic response to heat and the endothelium-dependent and endothelium-independent vasodilatation between the dorsum of the foot and the forearm in diabeticExpand
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Dorsalis pedis arterial bypass: durable limb salvage for foot ischemia in patients with diabetes mellitus.
PURPOSE Although the technical feasibility of pedal artery bypass for limb salvage is now well established, questions remain about its most appropriate use and its long-term durability. METHODS WeExpand
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