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Microtubule-associated protein tau in development, degeneration and protection of neurons
As a principal neuronal microtubule-associated protein, tau has been recognized to play major roles in promoting microtubule assembly and stabilizing the microtubules and to maintain the normal… Expand
O-GlcNAcylation regulates phosphorylation of tau: a mechanism involved in Alzheimer's disease.
- F. Liu, K. Iqbal, I. Grundke-Iqbal, G. Hart, C. Gong
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 20 July 2004
Microtubule-associated protein tau is abnormally hyperphosphorylated and aggregated into neurofibrillary tangles in brains of individuals with Alzheimer's disease (AD) and other tauopathies. Tau… Expand
Synthesis of a Brassica trigenomic allohexaploid (B. carinata × B. rapa) de novo and its stability in subsequent generations
- E. Tian, Y. Jiang, L. Chen, J. Zou, F. Liu, Jinling Meng
- Medicine, Biology
- Theoretical and Applied Genetics
- 4 July 2010
Allopolyploidy plays an important role in plant evolution and confers obvious advantages on crop growth and breeding compared to low ploidy levels. The present investigation was aimed at synthesising… Expand
Disagreeable Privacy Policies: Mismatches between Meaning and Users’ Understanding
Privacy policies are verbose, difficult to understand, take too long to read, and may be the least-read items on most websites even as users express growing concerns about information collection… Expand
A virus-like particle vaccine for coxsackievirus A16 potently elicits neutralizing antibodies that protect mice against lethal challenge.
Coxsackievirus A16 (CVA16) is one of the main causative agents of hand, foot and mouth disease (HFMD), which has been prevalent in the Asia-Pacific region over the last several years. However, no… Expand
The genomics of selection in dogs and the parallel evolution between dogs and humans.
The genetic bases of demographic changes and artificial selection underlying domestication are of great interest in evolutionary biology. Here we perform whole-genome sequencing of multiple grey… Expand
Design of the Anti-tuberculosis Drugs induced Adverse Reactions in China National Tuberculosis Prevention and Control Scheme Study (ADACS)
BackgroundMore than 1 million tuberculosis (TB) patients are receiving the standard anti-TB treatment provided by China National Tuberculosis Prevention and Control Scheme (CNTS) in China every year.… Expand
Diverse LEA (late embryogenesis abundant) and LEA-like genes and their responses to hypersaline stress in post-diapause embryonic development of Artemia franciscana.
- Gang Wu, Hangxiao Zhang, +5 authors W. Wang
- Biology, Medicine
- Comparative biochemistry and physiology. Part B…
- 1 September 2011
From post-diapause cysts of Artemia franciscana, we defined fourteen LEA (late embryogenesis abundant) and LEA-like genes, including four novel members (Afrlea1-5, Afrlea3-5, Afrlea3-like1 and… Expand
Electron Microscopic Studies of the Morphogenesis of Duck Enteritis Virus
Abstract The morphogenesis of duck enteritis virus (DEV) and distribution in vivo were observed by electron microscopy after ducks were infected experimentally with DEV virulent strain. The… Expand
The Minor Wall-Networks between Monolignols and Interlinked-Phenolics Predominantly Affect Biomass Enzymatic Digestibility in Miscanthus
Plant lignin is one of the major wall components that greatly contribute to biomass recalcitrance for biofuel production. In this study, total 79 representative Miscanthus germplasms were determined… Expand