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Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.
- M. Ackermann, S. Verleden, +11 authors D. Jonigk
- The New England journal of medicine
- 21 May 2020
BACKGROUND Progressive respiratory failure is the primary cause of death in the coronavirus disease 2019 (Covid-19) pandemic. Despite widespread interest in the pathophysiology of the disease,… Expand
Quantitative assessment of promoter hypermethylation during breast cancer development.
- U. Lehmann, F. Länger, H. Feist, S. Glöckner, B. Hasemeier, H. Kreipe
- Biology, Medicine
- The American journal of pathology
- 1 February 2002
The aberrant methylation of cytosine residues in the promoter region of growth regulatory genes is now widely recognized as an additional mechanism for gene inactivation in cancer cells. In this… Expand
Apoptosis of regulatory T lymphocytes is increased in chronic inflammatory bowel disease and reversed by anti-TNFα treatment
Background and aims Inappropriate immune responses contribute to the continuous stimulation of the intestinal immune system in chronic inflammatory bowel disease (IBD). Among several pathogenic… Expand
Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression.
- C. Bockmeyer, L. Maegel, +10 authors D. Jonigk
- The Journal of heart and lung transplantation…
- 1 July 2012
BACKGROUND Recent studies have revealed that microRNAs (miRNAs) play a key role in the control of angiogenesis and vascular remodeling. Specific miRNAs in plexiform vasculopathy of severe pulmonary… Expand
Important Role for CC Chemokine Ligand 2-Dependent Lung Mononuclear Phagocyte Recruitment to Inhibit Sepsis in Mice Infected with Streptococcus pneumoniae 1
- C. Winter, Wiebke Herbold, +5 authors U. Maus
- Biology, Medicine
- The Journal of Immunology
- 15 April 2009
The monocyte chemoattractant CCL2 is of major importance in inflammatory monocyte recruitment to the lungs in response to bacterial infection. Streptococcus pneumoniae is the most prevalent pathogen… Expand
[Pulmonary manifestations of inflammatory bowel disease].
Pulmonary disease is a rare complication of inflammatory bowel disease. Airway inflammation, interstitial lung disease and several other manifestations have been described, and typical symptoms are… Expand
The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group.
Until recently, the division of pulmonary carcinomas into small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the emergence of new… Expand
Undifferentiated embryonal sarcoma of the liver in adults
Undifferentiated embryonal sarcoma of the liver (UESL), a rare tumor that predominantly affects children, generally has been considered an aggressive neoplasm with an unfavorable prognosis. More… Expand
Identification of differentially expressed microRNAs in human male breast cancer
BackgroundThe discovery of small non-coding RNAs and the subsequent analysis of microRNA expression patterns in human cancer specimens have provided completely new insights into cancer biology.… Expand
Oncogenic Osteomalacia: Exact Tumor Localization by Co‐Registration of Positron Emission and Computed Tomography
- E. Hesse, Eckart Moessinger, +5 authors L. Bastian
- Journal of bone and mineral research : the…
- 2 October 2006
In oncogenic osteomalacia, the causative tumor is almost always difficult to find. A novel diagnostic approach is presented that facilitates a precise and rapid localization of the associated lesion… Expand